HitPredict

Interactor 1: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	1.00	0.527

Property	Details
Experiments	17274598
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1647 Hs			1 136
+	Hs
		846921 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		846989 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		846925 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		846743 SMCA2_HUMAN (1-1647): 0: 980: 71.69		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		828175 SMCA2_HUMAN (1-1647): 0: 980: 71.69		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Dm
		356069 BRM_DROME (211-1642): 0: 858: 53.26		H3_DROME (1-136): 3.73e-61: 186: 100.00
+	Hs
		229359 SMCA5_HUMAN (626-1631): 0: 835: 27.41		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Mm
		935460 SMCA5_MOUSE (626-1631): 0: 833: 27.41		H31_MOUSE (1-136): 1.98e-62: 189: 99.27
+	Hs
		229363 SMCA5_HUMAN (626-1631): 0: 835: 27.41		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		658647 SMCA1_HUMAN (639-1619): 0: 832: 28.82		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Mm
		952266 SMCA5_MOUSE (626-1631): 0: 833: 27.41		H32_MOUSE (1-136): 3.73e-61: 186: 100.00
+	Mm
		952763 SMCA5_MOUSE (626-1631): 0: 833: 27.41		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		658651 SMCA1_HUMAN (639-1619): 0: 832: 28.82		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Sp
		457191 SNF21_SCHPO (460-1587): 0: 806: 39.17		H31_SCHPO (1-136): 2.22e-59: 181: 91.91
+	Hs
		229341 SMCA5_HUMAN (626-1631): 0: 835: 27.41		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Hs
		658641 SMCA1_HUMAN (639-1619): 0: 832: 28.82		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Sc
		696239 STH1_YEAST (369-1559): 0: 789: 33.10		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Sc
		902117 ISW2_YEAST (565-1631): 0: 763: 25.02		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Sc
		603332 SNF2_YEAST (536-1569): 0: 757: 36.31		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Sc
		696197 STH1_YEAST (369-1559): 0: 789: 33.10		CENPA_YEAST (18-134): 1.58e-41: 139: 56.67