HitPredict

Interactor 1: MECP2 (P51608)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	30804502, 21278419
Identification Methods	affinity chromatography technology, x-ray crystallography
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 486 Hs			1 103
+	Hs
		309384 MBD4_HUMAN (99-480): 9.39e-45: 167: 20.05		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		328519 MBD3_HUMAN (93-249): 3.06e-43: 156: 26.88		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		918072 MBD2_HUMAN (75-249): 3.32e-38: 146: 28.65		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		918103 MBD1_HUMAN (95-220): 6.98e-31: 127: 31.78		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917667 TITIN_HUMAN (240-472): 1.28e-12: 72.8: 19.57		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917444 NIPBL_HUMAN (72-455): 1.96e-09: 62.4: 14.06		H4_HUMAN (1-103): 1.38e-48: 151: 100.00