Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1
Interactor 2: PELI1 (Q96FA3)
E3 ubiquitin-protein ligase pellino homolog 1 (Pellino-1) (EC 2.3.2.27) (Pellino-related intracellular-signaling molecule) (RING-type E3 ubiquitin transferase pellino homolog 1)
Gene: PELI1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.761 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26082489, 17675297, 19081057, 12496252, 16951688, 15917247, 28512203, 17997719, 19264966, 21204785, 16884718 |
| Identification Methods | affinity chromatography technology, pull down, enzymatic study, protein kinase assay, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, phosphorylation reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005829 - cytosol GO:0032496 - response to lipopolysaccharide GO:0043123 - positive regulation of canonical NF-kappaB signal transduction |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
