HitPredict

Interactor 1: CAV3 (P51637)
Caveolin-3 (M-caveolin)
Gene: CAV3

Interactor 2: FLNA (Q8BTM8)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	24952909
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030018 - Z disc GO:0044325 - transmembrane transporter binding GO:0044877 - protein-containing complex binding GO:0072659 - protein localization to plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 151 Mm			1 2647
+	Hs
		598019 CAV2_HUMAN (26-150): 3.46e-56: 174: 37.60		FLNA_HUMAN (1-2647): 0: 2433: 97.32
+	Mm
		848684 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		FLNB_MOUSE (28-2647): 0: 2354: 68.56
+	Mm
		848721 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		FLNC_MOUSE (8-2647): 0: 1231: 35.48
+	Mm
		69924 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		B1B0C7_MOUSE (286-2017): 8.18e-119: 426: 12.27
+	Mm
		848680 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		ACTN1_MOUSE (20-390): 1.09e-121: 411: 25.07
+	Mm
		548788 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		SPTB1_MOUSE (5-389): 2.63e-114: 409: 26.77
+	Mm
		848646 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		Q5FW75_MOUSE (3-390): 3.8e-121: 409: 24.75
+	Mm
		848660 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		SPTB2_MOUSE (1-389): 3.18e-111: 400: 26.50
+	Hs
		963297 CAV1_HUMAN (8-150): 4.14e-79: 233: 65.73		SPTB2_HUMAN (20-345): 7.06e-101: 366: 29.38
+	Mm
		848587 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		ACTN4_MOUSE (24-268): 1.36e-104: 361: 35.74
+	Mm
		57584 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		TITIN_MOUSE (255-866): 1.76e-10: 69.4: 10.51