HitPredict

Interactor 1: AFF1 (P51825)
AF4/FMR2 family member 1 (ALL1-fused gene from chromosome 4 protein) (Protein AF-4) (Protein FEL) (Proto-oncogene AF4)
Gene: AFF1

Interactor 2: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	21030982
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 136
+	Hs
		935344 AFF4_HUMAN (10-1208): 2.3e-90: 318: 34.44		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952682 AFF4_HUMAN (10-1208): 2.3e-90: 318: 34.44		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		934881 NIPBL_HUMAN (12-1005): 1.12e-50: 199: 12.27		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952407 NIPBL_HUMAN (12-1005): 1.12e-50: 199: 12.27		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		828271 NIPBL_HUMAN (12-1005): 1.12e-50: 199: 12.27		CENPA_HUMAN (9-133): 3.54e-44: 142: 49.24
+	Hs
		152625 KMT2D_HUMAN (357-1098): 8.96e-12: 72.4: 9.13		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		152661 KMT2D_HUMAN (357-1098): 8.96e-12: 72.4: 9.13		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		934763 MDC1_HUMAN (161-949): 1.95e-10: 67.6: 10.79		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952338 MDC1_HUMAN (161-949): 1.95e-10: 67.6: 10.79		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		935150 MINT_HUMAN (70-744): 7.76e-09: 62.7: 10.13		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		1057767 NCOA6_HUMAN (66-930): 2.88e-09: 63.9: 8.55		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		952573 MINT_HUMAN (70-744): 7.76e-09: 62.7: 10.13		H33_HUMAN (1-136): 4.53e-61: 185: 93.38