HitPredict

Interactor 1: LUM (P51884)
Lumican (Keratan sulfate proteoglycan lumican) (KSPG lumican)
Gene: LUM

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 338 Hs			1 193
+	Dm
		776889 SCRIB_DROME (122-338): 3.37e-33: 132: 21.08		RAC1_DROME (1-193): 2.11e-77: 231: 54.12
+	Hs
		900857 LGR4_HUMAN (20-258): 2.84e-25: 108: 22.43		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		925580 LGR4_HUMAN (20-258): 2.84e-25: 108: 22.43		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436488 LGR4_HUMAN (20-258): 2.84e-25: 108: 22.43		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		892569 LGR4_HUMAN (20-258): 2.84e-25: 108: 22.43		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		951411 FLRT3_HUMAN (162-338): 2.13e-18: 87.9: 24.16		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		195857 FLRT2_HUMAN (232-338): 3.03e-11: 66.4: 21.30		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		195859 FLRT2_HUMAN (232-338): 3.03e-11: 66.4: 21.30		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		195848 FLRT2_HUMAN (232-338): 3.03e-11: 66.4: 21.30		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		195860 FLRT2_HUMAN (232-338): 3.03e-11: 66.4: 21.30		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		195856 FLRT2_HUMAN (232-338): 3.03e-11: 66.4: 21.30		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		195849 FLRT2_HUMAN (232-338): 3.03e-11: 66.4: 21.30		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		195855 FLRT2_HUMAN (232-338): 3.03e-11: 66.4: 21.30		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		195858 FLRT2_HUMAN (232-338): 3.03e-11: 66.4: 21.30		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120219 FLRT2_HUMAN (232-338): 3.03e-11: 66.4: 21.30		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98