HitPredict

Interactor 1: CNN1 (P51911)
Calponin-1 (Basic calponin) (Calponin H1, smooth muscle)
Gene: CNN1

Interactor 2: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	2161834
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0015629 - actin cytoskeleton
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 377
+	Rn
		933100 CNN1_RAT (1-297): 2.71e-148: 419: 97.64		ACTS_RAT (1-377): 0: 605: 100.00
+	Hs
		891782 CNN3_HUMAN (4-279): 5.93e-130: 374: 72.30		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		932175 CNN3_HUMAN (4-279): 5.93e-130: 374: 72.30		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		891988 CNN2_HUMAN (1-285): 2.06e-120: 349: 63.76		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		932344 CNN2_HUMAN (1-285): 2.06e-120: 349: 63.76		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		741850 TAGL2_HUMAN (6-188): 7.76e-67: 208: 42.64		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		741855 TAGL2_HUMAN (6-188): 7.76e-67: 208: 42.64		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		741856 TAGL2_HUMAN (6-188): 7.76e-67: 208: 42.64		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Dm
		862565 Q9I7J0_DROME (26-188): 1.45e-56: 181: 41.57		ACT3_DROME (1-377): 0: 601: 92.84
+	Sp
		144980 IQG1_SCHPO (8-155): 1.3e-33: 132: 24.34		ACT_SCHPO (4-377): 0: 647: 89.04
+	Hs
		809232 IQGA1_HUMAN (7-172): 3.06e-41: 154: 16.85		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		809257 IQGA1_HUMAN (7-172): 3.06e-41: 154: 16.85		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		891748 IQGA2_HUMAN (6-172): 1.5e-40: 152: 16.20		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		892114 LIMC1_HUMAN (32-195): 1.08e-37: 143: 25.56		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		933037 LRCH3_HUMAN (3-137): 5.73e-33: 129: 23.53		ACTS_HUMAN (1-377): 0: 605: 100.00
+	Hs
		891926 LMO7_HUMAN (38-143): 9.1e-28: 115: 30.58		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		932285 LMO7_HUMAN (38-143): 9.1e-28: 115: 30.58		ACTC_HUMAN (1-377): 0: 604: 98.94