Protein: ZDHC6
Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Stearoyltransferase ZDHHC6) (EC 2.3.1.-) (Transmembrane protein H4) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) (Zinc finger protein 376)

Gene: ZDHC6, ZDHHC6
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q9H6R6

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
GO:0006612 - protein targeting to membrane
GO:0010636 - positive regulation of mitochondrial fusion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1434639

SG196
Protein O-mannose kinase

4

1

High-throughput

0.699

High

476515

STS
Steryl-sulfatase

2

2

High-throughput

0.628

High

967354

TSN5
Tetraspanin-5

3

14

High-throughput

0.609

High

1391356

WBP1
WW domain-binding protein 1

3

1

High-throughput

0.609

High

1435083

VSIG4
V-set and immunoglobulin domain-containing protein 4

3

2

High-throughput

0.609

High

1435082

SHLB2
Endophilin-B2

1

0

High-throughput

0.578

High

1435081

ZDH11
Palmitoyltransferase ZDHHC11

1

4

High-throughput

0.575

High

62160

KLRG2
Killer cell lectin-like receptor subfamily G member 2

2

3

High-throughput

0.574

High

252633

TSN2
Tetraspanin-2

2

12

High-throughput

0.574

High

1159107

C3AR
C3a anaphylatoxin chemotactic receptor

2

6

High-throughput

0.574

High

1419450

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

2

High-throughput

0.574

High

1153439

CD226
CD226 antigen

2

4

High-throughput

0.549

High

220421

LAT
Linker for activation of T-cells family member 1

1

2

High-throughput

0.536

High

376642

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

5

High-throughput

0.536

High

699132

CALX
Calnexin

1

0

High-throughput

0.513

High

161085

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

2

Small-scale

0.501

High

271602

ICOSL
ICOS ligand

1

2

High-throughput

0.489

High

369504

AACT
Alpha-1-antichymotrypsin

1

1

High-throughput

0.489

High

388145

ACHA
Acetylcholine receptor subunit alpha

1

4

High-throughput

0.489

High

457916

INVO
Involucrin

1

2

High-throughput

0.489

High

477471

CD63
CD63 antigen

1

13

High-throughput

0.489

High

762416

BTC
Probetacellulin [Cleaved into: Betacellulin

1

5

High-throughput

0.489

High

874866

SPB4
Serpin B4

1

1

High-throughput

0.489

High

1213702

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

3

High-throughput

0.489

High

1248398

I27RA
Interleukin-27 receptor subunit alpha

1

4

High-throughput

0.489

High

1256992

FBX50
F-box only protein 50

1

1

High-throughput

0.489

High

1308974

S22A9
Organic anion transporter 7

1

2

High-throughput

0.489

High

1330498

LRC52
Leucine-rich repeat-containing protein 52

1

4

High-throughput

0.489

High

1331637

LRTM2
Leucine-rich repeat and transmembrane domain-containing protein 2

1

4

High-throughput

0.489

High

218781

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

412615

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.457

High

710891

EPHB2
Ephrin type-B receptor 2

1

8

High-throughput

0.457

High

1034345

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

8

High-throughput

0.457

High

1147432

EPHA7
Ephrin type-A receptor 7

1

7

High-throughput

0.457

High

591369

CD44
CD44 antigen

1

1

High-throughput

0.445

High

1251188

ZNT10
Calcium/manganese antiporter SLC30A10

1

1

High-throughput

0.445

High

75725

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

2

High-throughput

0.437

High

69552

A2ML1
Alpha-2-macroglobulin-like protein 1

1

2

High-throughput

0.407

High

1393207

TM169
Transmembrane protein 169

1

3

High-throughput

0.407

High

1416643

PLVAP
Plasmalemma vesicle-associated protein

3

0

High-throughput

0.347

High

1126005

LRC32
Transforming growth factor beta activator LRRC32

3

0

High-throughput

0.345

High

161890

IMPA2
Inositol monophosphatase 2

1

0

High-throughput

0.279

Low

261657

CATL2
Cathepsin L2

1

0

High-throughput

0.279

Low

706313

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

1009723

NGAL
Neutrophil gelatinase-associated lipocalin

1

0

High-throughput

0.279

Low

1167051

ECSCR
Endothelial cell-specific chemotaxis regulator

1

0

High-throughput

0.279

Low

1193163

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

1

0

High-throughput

0.279

Low

1213834

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

1218798

BROX
BRO1 domain-containing protein BROX

1

0

High-throughput

0.279

Low

1272907

SYT13
Synaptotagmin-13

1

0

High-throughput

0.279

Low

1323574

CMTR1
Cap-specific mRNA

1

0

High-throughput

0.279

Low

1338068

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.279

Low

942293

CLD17
Claudin-17

1

0

High-throughput

0.269

Low

473083

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.249

Low

362067

AATM
Aspartate aminotransferase, mitochondrial

1

0

High-throughput

0.238

Low

1199096

CTL4
Choline transporter-like protein 4

1

0

High-throughput

0.232

Low

1204716

TAF7L
Transcription initiation factor TFIID subunit 7-like

1

0

High-throughput

0.232

Low

1380591

IGSF8
Immunoglobulin superfamily member 8

1

0

High-throughput

0.232

Low

1431233

S6A17
Sodium-dependent neutral amino acid transporter SLC6A17

1

0

High-throughput

0.232

Low

1059962

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

0

Small-scale

0.213

Low


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Last updated: 11Aug2025