HitPredict

Interactor 1: MEXB (P52002)
Multidrug resistance protein MexB (Multidrug-efflux transporter MexB)
Gene: MEXB

Interactor 2: MEXB (P52002)
Multidrug resistance protein MexB (Multidrug-efflux transporter MexB)
Gene: MEXB

Species: Pseudomonas aeruginosa PAO1

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	23812586
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ACR_tran~ACR_tran
Common GO terms	GO:0005886 - plasma membrane GO:0015562 - efflux transmembrane transporter activity GO:0042910 - xenobiotic transmembrane transporter activity GO:0046677 - response to antibiotic GO:0055085 - transmembrane transport
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1046 Pa			1 1046
+	Ec
		678727 ACRB_ECOLI (1-1017): 0: 1048: 70.95		ACRB_ECOLI (1-1017): 0: 1048: 70.95
+	Ec
		678728 ACRB_ECOLI (1-1017): 0: 1048: 70.95		MDTF_ECOLI (1-1018): 0: 986: 62.84
+	Ec
		741745 MDTF_ECOLI (1-1018): 0: 986: 62.84		MDTF_ECOLI (1-1018): 0: 986: 62.84
+	Ec
		940198 MDTC_ECOLI (2-1044): 0: 802: 28.15		MDTB_ECOLI (2-1044): 0: 771: 28.34
+	Ec
		940197 MDTB_ECOLI (2-1044): 0: 771: 28.34		MDTB_ECOLI (2-1044): 0: 771: 28.34
+	Bs
		191475 SWRC_BACSU (1-1039): 0: 690: 21.11		SWRC_BACSU (1-1039): 0: 690: 21.11
+	Bs
		191528 SWRC_BACSU (1-1039): 0: 690: 21.11		YDGH_BACSU (273-1028): 1.09e-105: 352: 11.82
+	Dm
		577329 PTC_DROME (314-527): 1.17e-25: 116: 13.36		PTC_DROME (314-527): 1.17e-25: 116: 13.36
+	Ec
		743242 CUSA_ECOLI (530-1033): 1.55e-22: 106: 16.89		CUSA_ECOLI (530-1033): 1.55e-22: 106: 16.89
+	Hs
		1044329 PTC1_HUMAN (298-504): 8.69e-12: 71.8: 13.00		PTC1_HUMAN (298-504): 8.69e-12: 71.8: 13.00