HitPredict

Interactor 1: ACTZ (P45889)
Actin-related protein 1 (Actin-like protein 1) (Actin-like protein 87C)
Gene: Arp1

Interactor 2: DCTN2 (Q7K2D2)
Dynactin subunit 2 (Dynamitin) (Dynactin 2 p50 subunit)
Gene: DCTN2-p50

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Dynamitin
Common GO terms	GO:0005869 - dynactin complex GO:0008090 - retrograde axonal transport GO:1904115 - axon cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 376 Dm			1 380
+	Hs
		958431 ACTZ_HUMAN (1-376): 0: 649: 79.26		DCTN2_HUMAN (1-376): 2.52e-151: 434: 32.01
+	Hs
		837221 ACTY_HUMAN (1-376): 0: 641: 77.13		DCTN2_HUMAN (1-376): 2.52e-151: 434: 32.01
+	Hs
		952800 ACTB_HUMAN (7-376): 0: 582: 53.48		DCTN2_HUMAN (1-376): 2.52e-151: 434: 32.01
+	Hs
		993167 ACTG_HUMAN (6-376): 0: 582: 53.60		DCTN2_HUMAN (1-376): 2.52e-151: 434: 32.01
+	Hs
		995578 ACTC_HUMAN (5-376): 0: 577: 53.19		DCTN2_HUMAN (1-376): 2.52e-151: 434: 32.01
+	Ce
		1066909 Q9NA98_CAEEL (4-376): 0: 519: 65.42		DCTN2_CAEEL (16-376): 2.8e-109: 325: 21.53