HitPredict

Interactor 1: CBX5 (P45973)
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Interactor 2: ZN678 (Q5SXM1)
Zinc finger protein 678
Gene: ZNF678

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	27705803
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 525
+	Hs
		853290 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN569_HUMAN (3-484): 0: 689: 49.69
+	Hs
		853329 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN227_HUMAN (14-524): 0: 665: 43.91
+	Hs
		853229 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZNF45_HUMAN (48-525): 0: 656: 51.15
+	Hs
		1097401 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZN227_HUMAN (14-524): 0: 665: 43.91
+	Hs
		1036605 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZNF45_HUMAN (48-525): 0: 656: 51.15
+	Hs
		70557 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZN850_HUMAN (46-524): 0: 644: 53.03
+	Hs
		776911 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZNF93_HUMAN (3-488): 0: 631: 55.65
+	Hs
		67044 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN726_HUMAN (3-456): 0: 605: 58.46
+	Hs
		67018 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN729_HUMAN (3-470): 0: 603: 53.43
+	Hs
		1097425 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZN615_HUMAN (2-455): 0: 608: 47.47
+	Hs
		599990 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZNF16_HUMAN (88-524): 0: 606: 48.97
+	Hs
		1051147 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZNF91_HUMAN (28-524): 0: 604: 58.84
+	Hs
		67023 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZN729_HUMAN (3-470): 0: 603: 53.43
+	Hs
		853287 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		Z585B_HUMAN (177-525): 8.41e-147: 441: 49.57
+	Hs
		1097442 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZN420_HUMAN (246-525): 9.71e-146: 436: 61.43
+	Hs
		853307 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		Z585A_HUMAN (289-525): 1.03e-86: 284: 43.88
+	Hs
		853283 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN568_HUMAN (8-208): 7.65e-61: 213: 38.12
+	Hs
		1097324 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZN568_HUMAN (8-208): 7.65e-61: 213: 38.12
+	Hs
		70999 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN724_HUMAN (7-124): 1.82e-15: 81.2: 23.53
+	Hs
		1097380 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZN534_HUMAN (363-525): 2.94e-19: 93.2: 36.20