HitPredict

Interactor 1: IMA1 (P52292)
Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)
Gene: KPNA2

Interactor 2: NF2L2 (Q16236)
Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nrf-2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2)
Gene: NFE2L2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.53	0.60	0.568

Property	Details
Experiments	32911434
Identification Methods	two hybrid, two hybrid array, luminescence based mammalian interactome mapping
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 529 Hs			1 605
+	Hs
		134906 IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38		NF2L2_HUMAN (1-605): 0: 560: 100.00
+	Hs
		131445 IMA4_HUMAN (4-529): 6.93e-148: 436: 49.06		NF2L2_HUMAN (1-605): 0: 560: 100.00
+	Hs
		401677 IMA1_HUMAN (1-529): 6.78e-164: 477: 100.00		JUN_HUMAN (240-572): 5.59e-55: 191: 13.61
+	Hs
		134825 IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38		JUN_HUMAN (240-572): 5.59e-55: 191: 13.61
+	Hs
		853322 IMA1_HUMAN (1-529): 6.78e-164: 477: 100.00		CR3L3_HUMAN (291-571): 2.11e-35: 141: 13.17
+	Hs
		853532 IMA1_HUMAN (1-529): 6.78e-164: 477: 100.00		MAFB_HUMAN (434-581): 4.01e-34: 134: 19.60
+	Dm
		593987 Q9V455_DROME (1-529): 3.23e-136: 406: 47.55		CNC_DROME (349-598): 8.62e-48: 182: 33.33
+	Dm
		593971 IMA_DROME (6-529): 2.4e-121: 368: 48.30		CNC_DROME (349-598): 8.62e-48: 182: 33.33