HitPredict

Interactor 1: IMA1 (P52292)
Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)
Gene: KPNA2

Interactor 2: RGPD5 (Q99666)
RANBP2-like and GRIP domain-containing protein 5/6 (Ran-binding protein 2-like 1/2) (RanBP2-like 1/2) (RanBP2L1) (RanBP2L2) (Sperm membrane protein BS-63)
Gene: RGPD5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0006607 - NLS-bearing protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 529 Hs			1 1765
+	Hs
		152769 IMA1_HUMAN (1-529): 6.78e-164: 477: 100.00		RGPD8_HUMAN (1-1765): 0: 2162: 99.49
+	Hs
		63862 IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38		RGPD3_HUMAN (1-1757): 0: 2109: 95.56
+	Hs
		134921 IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38		RGPD4_HUMAN (1-1757): 0: 2104: 95.05
+	Hs
		853515 IMA1_HUMAN (1-529): 6.78e-164: 477: 100.00		NUP50_HUMAN (1124-1466): 1.62e-33: 138: 18.68
+	Hs
		1192291 Q7Z726_HUMAN (1-529): 1.3e-163: 476: 99.81		NUP50_HUMAN (1124-1466): 1.62e-33: 138: 18.68
+	Hs
		834693 IMA1_HUMAN (1-529): 6.78e-164: 477: 100.00		RBP2_HUMAN (686-1191): 1.36e-30: 134: 23.67
+	Hs
		134978 IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38		NUP50_HUMAN (1124-1466): 1.62e-33: 138: 18.68
+	Hs
		134854 IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38		RBP2_HUMAN (686-1191): 1.36e-30: 134: 23.67
+	Hs
		134964 IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38		RANB3_HUMAN (934-1509): 2.61e-31: 133: 14.60
+	Hs
		131527 IMA4_HUMAN (4-529): 6.93e-148: 436: 49.06		NUP50_HUMAN (1124-1466): 1.62e-33: 138: 18.68
+	Hs
		131404 IMA4_HUMAN (4-529): 6.93e-148: 436: 49.06		RBP2_HUMAN (686-1191): 1.36e-30: 134: 23.67
+	Sc
		691660 IMA1_YEAST (2-529): 3.96e-141: 419: 43.83		NUP2_YEAST (698-1171): 1.67e-33: 142: 18.33
+	At
		1280910 IMPA1_ARATH (1-529): 3.69e-156: 457: 45.00		NU50A_ARATH (793-1198): 3.2e-22: 103: 16.87
+	At
		138100 IMPA3_ARATH (1-529): 4.06e-156: 457: 43.95		NU50A_ARATH (793-1198): 3.2e-22: 103: 16.87
+	Hs
		134843 IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38		RANG_HUMAN (1014-1207): 2.48e-27: 113: 37.88
+	At
		97810 IMPA2_ARATH (1-529): 1.12e-155: 456: 44.47		NU50A_ARATH (793-1198): 3.2e-22: 103: 16.87
+	Hs
		238747 IMA7_HUMAN (1-528): 1.97e-141: 420: 45.37		NUP50_HUMAN (1124-1466): 1.62e-33: 138: 18.68
+	At
		285384 IMPA4_ARATH (1-529): 9.28e-155: 454: 43.57		NU50A_ARATH (793-1198): 3.2e-22: 103: 16.87
+	At
		1320502 IMPA6_ARATH (1-529): 1.15e-152: 448: 42.46		NU50A_ARATH (793-1198): 3.2e-22: 103: 16.87
+	Hs
		131396 IMA4_HUMAN (4-529): 6.93e-148: 436: 49.06		RANG_HUMAN (1014-1207): 2.48e-27: 113: 37.88