Interactor 1: UBP5 (P45974)
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)
Gene: USP5
Interactor 2: PDCD1 (Q15116)
Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279)
Gene: PDCD1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 1.00 | 0.747 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 37208329 |
| Identification Methods | pull down, enzymatic study, affinity chromatography technology, unspecified method |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | UCH~V-set |
| Common GO terms | GO:0002841 - negative regulation of T cell mediated immune response to tumor cell |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
