HitPredict - High confidence protein-protein interactions

Protein: PDCD1
Programmed cell death protein 1 (Protein PD-1) (mPD-1) (CD antigen CD279)

Gene: PDCD1
Organism: Mus musculus
Interactions: 7
UniProt ID: Q02242

Gene Ontology (top 5):
GO:0001783 - B cell apoptotic process
GO:0002250 - adaptive immune response
GO:0002644 - negative regulation of tolerance induction
GO:0002841 - negative regulation of T cell mediated immune response to tumor cell
GO:0002903 - negative regulation of B cell apoptotic process

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1036038	PD1L1 Programmed cell death 1 ligand 1	5	4	Small-scale	0.912	High
1036040	PD1L2 Programmed cell death 1 ligand 2	2	3	Small-scale	0.789	High
662965	MDM2 E3 ubiquitin-protein ligase Mdm2	1	1	Small-scale	0.553	High
940739	UBP5 Ubiquitin carboxyl-terminal hydrolase 5	1	1	Small-scale	0.553	High
858589	PDCD2 Programmed cell death protein 2	1	0	Small-scale	0.261	Low
1036037	IRF9 Interferon regulatory factor 9	1	0	Small-scale	0.249	Low
1036039	TBX21 T-box transcription factor TBX21	1	0	Small-scale	0.249	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025