Protein: UBP5
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)

Gene: UBP5, Usp5
Organism: Mus musculus
Interactions: 20
UniProt ID: P56399

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0006508 - proteolysis
GO:0008270 - zinc ion binding
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043130 - ubiquitin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

508993

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

2

20

Small-scale

0.696

High

940740

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

18

High-throughput

0.618

High

940742

ISG15
Ubiquitin-like protein ISG15

1

20

Small-scale

0.579

High

940739

PDCD1
Programmed cell death protein 1

1

1

Small-scale

0.553

High

940743

FACD2
Fanconi anemia group D2 protein homolog

1

3

High-throughput

0.553

High

940745

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.553

High

940747

EED
Polycomb protein EED

1

16

High-throughput

0.553

High

478503

ITB1
Integrin beta-1

1

10

High-throughput

0.457

High

98190

E9Q6P9
Voltage-dependent T-type calcium channel subunit alpha-1H

1

1

Small-scale

0.437

High

108543

G3X9H5
Huntingtin

1

1

High-throughput

0.437

High

205003

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

1

High-throughput

0.437

High

530736

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.437

High

712508

CASP1
Caspase-1

1

3

Small-scale

0.437

High

940741

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

1

High-throughput

0.437

High

940744

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

6

High-throughput

0.437

High

940746

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

3

Small-scale

0.437

High

940748

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

9

Small-scale

0.437

High

940749

ATAD1
Outer mitochondrial transmembrane helix translocase

1

8

Small-scale

0.437

High

940750

ASC
Apoptosis-associated speck-like protein containing a CARD

1

6

Small-scale

0.437

High

551396

A4
Amyloid-beta precursor protein

1

5

Small-scale

0.373

High


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Last updated: 11Aug2025