HitPredict

Interactor 1: RPAB3 (P52434)
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerase II subunit H) (DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide) (RPB17) (RPB8 homolog) (hRPB8)
Gene: POLR2H

Interactor 2: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.735

Property	Details
Experiments	26496610, 28514442, 9201987, 33961781, 24981860, 35271311
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003697 - single-stranded DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005665 - RNA polymerase II, core complex GO:0006366 - transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 150 Hs			1 172
+	Hs
		87443 C9JLU1_HUMAN (1-148): 4.62e-77: 227: 100.00		RPB7_HUMAN (1-172): 1.48e-76: 227: 100.00
+	Hs
		854401 RPAB3_HUMAN (1-150): 1.61e-78: 231: 100.00		RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72
+	Sc
		593305 RPAB3_YEAST (1-147): 2.38e-48: 154: 35.07		RPB7_YEAST (1-171): 4.45e-63: 193: 42.78
+	Sp
		145820 RPAB3_SCHPO (4-147): 5.15e-41: 135: 36.81		RPB7_SCHPO (2-171): 1.24e-67: 205: 49.42
+	Sc
		593307 RPAB3_YEAST (1-147): 2.38e-48: 154: 35.07		RPC8_YEAST (1-158): 1.07e-49: 160: 19.39