HitPredict

Interactor 1: RPB11 (P52435)
DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit)
Gene: POLR2J

Interactor 2: GPN1 (Q9HCN4)
GPN-loop GTPase 1 (EC 3.6.5.-) (MBD2-interacting protein) (MBDin) (RNAPII-associated protein 4) (XPA-binding protein 1)
Gene: GPN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	24981860, 33961781, 35271311, 17643375
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 374
+	Hs
		484483 RPAC2_HUMAN (12-116): 3.57e-40: 131: 30.56		GPN1_HUMAN (1-374): 0: 529: 100.00
+	Sc
		757141 RPB11_YEAST (1-110): 4.2e-45: 144: 50.00		GPN1_YEAST (22-370): 4.42e-152: 435: 50.41
+	Hs
		854473 RPB11_HUMAN (1-117): 1.88e-53: 164: 100.00		GPN2_HUMAN (12-261): 1.75e-106: 316: 23.85
+	Hs
		1325961 RPB1B_HUMAN (1-109): 7.3e-48: 150: 95.41		GPN2_HUMAN (12-261): 1.75e-106: 316: 23.85
+	Hs
		854494 RPB11_HUMAN (1-117): 1.88e-53: 164: 100.00		GPN3_HUMAN (20-285): 1.71e-96: 290: 25.00
+	Sc
		757159 RPB11_YEAST (1-110): 4.2e-45: 144: 50.00		GPN3_YEAST (20-271): 3.94e-93: 281: 23.86
+	Hs
		484496 RPAC2_HUMAN (12-116): 3.57e-40: 131: 30.56		GPN3_HUMAN (20-285): 1.71e-96: 290: 25.00