Protein: KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform (Phosphorylase kinase alpha L subunit)

Gene: KPB2, PHKA2
Organism: Homo sapiens
Interactions: 69
UniProt ID: P46019

Gene Ontology (top 5):
GO:0004689 - phosphorylase kinase activity
GO:0005516 - calmodulin binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005964 - phosphorylase kinase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

585772

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

10

8

High-throughput

0.978

High

854448

KPBB
Phosphorylase b kinase regulatory subunit beta

3

3

High-throughput

0.858

High

270784

ROCK2
Rho-associated protein kinase 2

1

1

High-throughput

0.691

High

854422

KPB1
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform

1

3

High-throughput

0.691

High

854432

ROCK1
Rho-associated protein kinase 1

1

1

High-throughput

0.691

High

854436

PKN2
Serine/threonine-protein kinase N2

1

1

High-throughput

0.691

High

854438

PHKG1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform

1

8

High-throughput

0.691

High

854445

DOK4
Docking protein 4

3

1

High-throughput

0.667

High

854453

VRK1
Serine/threonine-protein kinase VRK1

1

0

High-throughput

0.656

High

400452

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

Small-scale

0.621

High

138813

STK25
Serine/threonine-protein kinase 25

1

4

High-throughput

0.618

High

854424

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

4

High-throughput

0.618

High

854430

STK4
Serine/threonine-protein kinase 4

1

4

High-throughput

0.618

High

854431

STK3
Serine/threonine-protein kinase 3

1

4

High-throughput

0.618

High

190706

MPPD1
Metallophosphoesterase domain-containing protein 1

3

2

High-throughput

0.609

High

438952

DCUP
Uroporphyrinogen decarboxylase

2

0

High-throughput

0.580

High

342786

HERC2
E3 ubiquitin-protein ligase HERC2

2

3

High-throughput

0.571

High

854428

CDK3
Cyclin-dependent kinase 3

1

1

High-throughput

0.553

High

854456

STK33
Serine/threonine-protein kinase 33

1

3

High-throughput

0.553

High

134593

SAP18
Histone deacetylase complex subunit SAP18

1

2

High-throughput

0.536

High

171194

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

0

High-throughput

0.513

High

192010

GLYG2
Glycogenin-2

1

0

High-throughput

0.513

High

254339

CC14B
Dual specificity protein phosphatase CDC14B

1

0

High-throughput

0.513

High

339325

MET18
Histidine protein methyltransferase 1 homolog

1

0

High-throughput

0.513

High

540348

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.513

High

732471

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.513

High

854423

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.513

High

854434

MESD
LRP chaperone MESD

1

0

High-throughput

0.513

High

854435

TOM34
Mitochondrial import receptor subunit TOM34

1

0

High-throughput

0.513

High

854437

UBE2S
Ubiquitin-conjugating enzyme E2 S

1

0

High-throughput

0.513

High

854443

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

0

High-throughput

0.513

High

854451

CCD43
Coiled-coil domain-containing protein 43

1

0

High-throughput

0.513

High

854459

CHM1A
Charged multivesicular body protein 1a

1

0

High-throughput

0.513

High

854461

SBDS
Ribosome maturation protein SBDS

1

0

High-throughput

0.513

High

854462

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

854440

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

854425

FGF12
Fibroblast growth factor 12

1

1

High-throughput

0.489

High

854427

FOXK1
Forkhead box protein K1

1

1

High-throughput

0.489

High

181860

SMAD9
Mothers against decapentaplegic homolog 9

1

0

High-throughput

0.486

High

124582

EYA2
Protein phosphatase EYA2

1

2

High-throughput

0.479

High

279301

TULP3
Tubby-related protein 3

1

2

High-throughput

0.479

High

413369

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

854426

STXB1
Syntaxin-binding protein 1

1

1

High-throughput

0.479

High

854429

UBE3A
Ubiquitin-protein ligase E3A

1

2

Small-scale

0.479

High

854433

CUL4B
Cullin-4B

1

2

High-throughput

0.479

High

854442

CEP57
Centrosomal protein of 57 kDa

1

1

High-throughput

0.479

High

854447

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

854455

GCP2
Gamma-tubulin complex component 2

1

2

High-throughput

0.479

High

854458

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

854460

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

447995

ITAV
Integrin alpha-V

1

0

Small-scale

0.458

High

854439

MIDN
Midnolin

1

0

High-throughput

0.458

High

854441

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

516319

CALM1
Calmodulin-1

1

8

High-throughput

0.445

High

516391

CALM2
Calmodulin-2

1

8

High-throughput

0.445

High

516475

CALM3
Calmodulin-3

1

8

High-throughput

0.445

High

538735

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

1

High-throughput

0.445

High

844732

EAA1
Excitatory amino acid transporter 1

1

2

High-throughput

0.445

High

293343

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

166267

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.426

High

854446

S39A7
Zinc transporter SLC39A7

1

2

High-throughput

0.407

High

854450

TEAN2
Transcription elongation factor A N-terminal and central domain-containing protein 2

2

0

High-throughput

0.328

High

286436

WBP4
WW domain-binding protein 4

1

0

High-throughput

0.279

Low

854449

BT3L4
Transcription factor BTF3 homolog 4

1

0

High-throughput

0.279

Low

854452

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.279

Low

854454

CMS1
Protein CMSS1

1

0

High-throughput

0.279

Low

854457

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.279

Low

854444

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.269

Low

854463

ARL5A
ADP-ribosylation factor-like protein 5A

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025