HitPredict

Interactor 1: RPB11 (P52435)
DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit)
Gene: POLR2J

Interactor 2: RPC10 (Q9Y2Y1)
DNA-directed RNA polymerase III subunit RPC10 (RNA polymerase III subunit C10) (DNA-directed RNA polymerase III subunit K) (RNA polymerase III 12.5 kDa subunit) (RPC12.5) (RNA polymerase III subunit C11) (HsC11p) (RPC11) (hRPC11)
Gene: POLR3K

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003899 - DNA-directed 5'-3' RNA polymerase activity GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 108
+	Hs
		738831 RPB11_HUMAN (1-117): 1.88e-53: 164: 100.00		RPB9_HUMAN (2-108): 1.17e-36: 122: 26.79
+	Hs
		484501 RPAC2_HUMAN (12-116): 3.57e-40: 131: 30.56		RPC10_HUMAN (1-108): 3.11e-41: 133: 100.00
+	Sc
		655559 RPB11_YEAST (1-110): 4.2e-45: 144: 50.00		RPB9_YEAST (2-107): 4.43e-31: 107: 26.36
+	Hs
		854489 RPB11_HUMAN (1-117): 1.88e-53: 164: 100.00		RPA12_HUMAN (2-108): 2.44e-22: 86: 24.55
+	Hs
		854420 RPB11_HUMAN (1-117): 1.88e-53: 164: 100.00		TCEA2_HUMAN (32-107): 1.23e-18: 80.2: 27.63
+	Sc
		655651 RPAC2_YEAST (13-110): 5.03e-33: 114: 33.33		RPC10_YEAST (1-108): 3.54e-31: 107: 50.44
+	Sc
		425468 RPB11_YEAST (1-110): 4.2e-45: 144: 50.00		TFS2_YEAST (27-107): 2.37e-17: 76.7: 31.71
+	Sc
		655595 RPAC2_YEAST (13-110): 5.03e-33: 114: 33.33		RPA12_YEAST (2-107): 4.82e-19: 77.5: 23.73