HitPredict

Interactor 1: CRKL (P46109)
Crk-like protein
Gene: CRKL

Interactor 2: SPN90 (Q9NZQ3)
NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (54 kDa vimentin-interacting protein) (VIP54) (90 kDa SH3 protein interacting with Nck) (AF3p21) (Dia-interacting protein 1) (DIP-1) (Diaphanous protein-interacting protein) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-interacting protein)
Gene: NCKIPSD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	SH2~SH3_1, SH3_1~SH3_1, SH3_1~SH3_2
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 303 Hs			1 722
+	Mm
		868846 CRKL_MOUSE (1-303): 5.53e-70: 220: 96.70		SPN90_MOUSE (1-722): 0: 1138: 88.37
+	Hs
		855784 CRK_HUMAN (3-302): 1.42e-51: 173: 54.89		SPN90_HUMAN (1-722): 0: 1137: 100.00
+	Hs
		619120 PLCG1_HUMAN (5-253): 8.29e-28: 115: 16.60		SPN90_HUMAN (1-722): 0: 1137: 100.00
+	Hs
		987988 GRB2_HUMAN (126-295): 3.56e-23: 96.8: 15.89		SPN90_HUMAN (1-722): 0: 1137: 100.00
+	Hs
		222219 NCK2_HUMAN (13-98): 9.64e-18: 84.4: 29.89		SPN90_HUMAN (1-722): 0: 1137: 100.00
+	Hs
		1453435 ITSN2_HUMAN (73-297): 1.66e-16: 82.1: 16.89		SPN90_HUMAN (1-722): 0: 1137: 100.00
+	Hs
		594119 NCK1_HUMAN (85-196): 2.66e-16: 80.2: 22.81		SPN90_HUMAN (1-722): 0: 1137: 100.00