HitPredict

Interactor 1: EFNA5 (P52803)
Ephrin-A5 (AL-1) (EPH-related receptor tyrosine kinase ligand 7) (LERK-7)
Gene: EFNA5

Interactor 2: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 10366629, 28514442, 33961781, 36736316, 22036564
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, comigration in sds page
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ephrin~Ephrin_lbd
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005886 - plasma membrane
GO:0007411 - axon guidance
GO:0022407 - regulation of cell-cell adhesion
GO:0031290 - retinal ganglion cell axon guidance
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 228
Hs

1 998
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024