HitPredict

Interactor 1: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	32296183, 33277362, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, validated two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UBA~UBA, UBA~ubiquitin, ubiquitin~ubiquitin, UBA~XPC-binding
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0031593 - polyubiquitin modification-dependent protein binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 409 Hs			1 624
+	Hs
		931613 RD23A_HUMAN (1-409): 9.16e-94: 287: 56.72		UBQL2_HUMAN (1-624): 1.53e-153: 457: 100.00
+	Hs
		931617 RD23A_HUMAN (1-409): 9.16e-94: 287: 56.72		UBQL1_HUMAN (1-624): 1.17e-146: 439: 71.52
+	Hs
		931607 RD23A_HUMAN (1-409): 9.16e-94: 287: 56.72		UBQL4_HUMAN (22-624): 2.7e-124: 382: 54.55
+	Hs
		1459882 UBQL1_HUMAN (1-404): 1.26e-57: 200: 13.72		UBQL2_HUMAN (1-624): 1.53e-153: 457: 100.00
+	Hs
		1462096 UBQL1_HUMAN (1-404): 1.26e-57: 200: 13.72		UBQL1_HUMAN (1-624): 1.17e-146: 439: 71.52
+	Hs
		1448810 UBQL1_HUMAN (1-404): 1.26e-57: 200: 13.72		UBQL4_HUMAN (22-624): 2.7e-124: 382: 54.55
+	Hs
		931670 RD23B_HUMAN (1-409): 1.32e-125: 370: 100.00		DDI2_HUMAN (43-314): 7.11e-52: 185: 14.59
+	Hs
		856606 RD23A_HUMAN (1-409): 9.16e-94: 287: 56.72		BAG6_HUMAN (21-580): 5.18e-53: 198: 15.23
+	Hs
		931541 RD23A_HUMAN (1-409): 9.16e-94: 287: 56.72		DDI2_HUMAN (43-314): 7.11e-52: 185: 14.59
+	Hs
		931491 RD23A_HUMAN (1-409): 9.16e-94: 287: 56.72		RL40_HUMAN (33-112): 7.23e-34: 127: 30.86
+	Hs
		856984 UBQL1_HUMAN (1-404): 1.26e-57: 200: 13.72		BAG6_HUMAN (21-580): 5.18e-53: 198: 15.23
+	Hs
		931490 RD23A_HUMAN (1-409): 9.16e-94: 287: 56.72		RS27A_HUMAN (33-119): 4.51e-24: 100: 27.27
+	Sp
		268139 RHP23_SCHPO (1-409): 1.79e-77: 245: 34.43		DSK2_SCHPO (33-240): 1.39e-27: 116: 23.26
+	Sc
		743999 RAD23_YEAST (1-407): 2.13e-72: 233: 28.41		DSK2_YEAST (32-239): 1.17e-31: 128: 31.19
+	Zm
		83796 B6TNT9_MAIZE (2-406): 5.62e-58: 199: 14.18		K7UR93_MAIZE (33-313): 1.12e-39: 152: 14.39
+	Dm
		583697 Q9V3W9_DROME (1-408): 5.4e-89: 277: 36.75		RS27A_DROME (33-103): 7.02e-13: 68.4: 33.33
+	Hs
		987499 UBQL1_HUMAN (1-404): 1.26e-57: 200: 13.72		RL40_HUMAN (33-112): 7.23e-34: 127: 30.86
+	Hs
		1259229 UBQL1_HUMAN (1-404): 1.26e-57: 200: 13.72		TMUB2_HUMAN (6-143): 8.36e-26: 110: 25.00
+	Hs
		987268 UBQL1_HUMAN (1-404): 1.26e-57: 200: 13.72		RS27A_HUMAN (33-119): 4.51e-24: 100: 27.27
+	Ce
		113201 UBQL_CAEEL (1-404): 1.92e-58: 200: 14.68		RL40_CAEEL (33-103): 7.53e-13: 67.7: 33.33