HitPredict

Interactor 1: CAZA1 (P52907)
F-actin-capping protein subunit alpha-1 (CapZ alpha-1)
Gene: CAPZA1

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	27173435, 33961781
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 1278
+	Hs
		813024 CAZA2_HUMAN (1-286): 6.84e-159: 445: 86.71		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Ss
		49076 CAZA1_PIG (1-286): 1.08e-162: 454: 97.90		MYH2_PIG (680-1266): 6.72e-25: 115: 9.90
+	Hs
		725107 CAZA2_HUMAN (1-286): 6.84e-159: 445: 86.71		MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13
+	Hs
		675134 CAZA2_HUMAN (1-286): 6.84e-159: 445: 86.71		CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32
+	Hs
		724728 CAZA1_HUMAN (1-286): 1.77e-164: 459: 100.00		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54
+	Hs
		724703 CAZA2_HUMAN (1-286): 6.84e-159: 445: 86.71		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54