HitPredict

Interactor 1: YGZ2 (P53066)
Ankyrin repeat-containing protein YGL242C
Gene: YGL242C

Interactor 2: MYO5 (Q04439)
Myosin-5 (Actin-dependent myosin-I MYO5) (Class I unconventional myosin MYO5) (Type I myosin MYO5)
Gene: MYO5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.80	0.765

Property	Details
Experiments	16554755, 18467557, 16429126
Identification Methods	affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 181 Sc			1 1219
+	Sc
		730579 YGZ2_YEAST (1-181): 2.29e-53: 169: 100.00		MYO3_YEAST (1-1205): 0: 1087: 72.08
+	Sp
		1350802 YIT2_SCHPO (1-151): 8.1e-49: 157: 39.74		MYO1_SCHPO (1-1219): 0: 1043: 51.57
+	Mm
		223297 ILK_MOUSE (1-152): 6.23e-33: 123: 19.08		MYH10_MOUSE (2-1105): 0: 1014: 24.11
+	Hs
		862127 DAPK1_HUMAN (1-169): 1.81e-27: 109: 10.06		MYO5B_HUMAN (23-1094): 0: 1009: 24.77
+	Hs
		1021717 ANR50_HUMAN (64-175): 5.5e-12: 65.3: 9.82		MYO1E_HUMAN (24-1145): 0: 1052: 36.98
+	Hs
		724782 ANK2_HUMAN (93-175): 7.09e-12: 64.9: 15.66		MYH9_HUMAN (7-1119): 0: 1017: 23.96
+	Hs
		725139 ANK2_HUMAN (93-175): 7.09e-12: 64.9: 15.66		MYH10_HUMAN (2-1099): 0: 1013: 24.07
+	Hs
		117643 DAPK1_HUMAN (1-169): 1.81e-27: 109: 10.06		MYO1C_HUMAN (31-736): 0: 570: 41.82
+	Hs
		214538 DAPK1_HUMAN (1-169): 1.81e-27: 109: 10.06		MYO1B_HUMAN (36-730): 5.19e-171: 538: 39.72
+	Hs
		297344 ILK_HUMAN (1-152): 4.09e-33: 123: 19.08		MYO1D_HUMAN (35-766): 3.11e-167: 524: 39.69
+	Hs
		297324 DAPK1_HUMAN (1-169): 1.81e-27: 109: 10.06		MYO1D_HUMAN (35-766): 3.11e-167: 524: 39.69
+	Hs
		214553 ANK2_HUMAN (93-175): 7.09e-12: 64.9: 15.66		MYO1B_HUMAN (36-730): 5.19e-171: 538: 39.72
+	Hs
		297337 ANK2_HUMAN (93-175): 7.09e-12: 64.9: 15.66		MYO1D_HUMAN (35-766): 3.11e-167: 524: 39.69
+	Hs
		1357029 HECD1_HUMAN (1-148): 1.43e-33: 127: 17.57		MYO5A_HUMAN (712-1118): 1.31e-10: 68.2: 9.31
+	Hs
		965180 ANK2_HUMAN (93-175): 7.09e-12: 64.9: 15.66		MYO5A_HUMAN (712-1118): 1.31e-10: 68.2: 9.31