Protein: RL28
Large ribosomal subunit protein uL15 (60S ribosomal protein L28) (L27a) (L29) (RP44) (RP62) (YL24)

Gene: RL28, RPL28
Organism: Saccharomyces cerevisiae S288C
Interactions: 163
UniProt ID: P02406

Gene Ontology (top 5):
GO:0002181 - cytoplasmic translation
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

383248

RL18B
Large ribosomal subunit protein eL18B

2

1

High-throughput

0.754

High

383364

RQC1
Ribosome quality control complex subunit 1

3

0

Small-scale

0.628

High

383253

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.618

High

383223

HSP82
ATP-dependent molecular chaperone HSP82

3

0

High-throughput

0.613

High

383255

CAF20
Cap-associated protein CAF20

3

0

Small-scale

0.613

High

383347

NOP15
Ribosome biogenesis protein 15

2

0

High-throughput

0.585

High

383250

SSBP1
Single-stranded nucleic acid-binding protein

2

2

High-throughput

0.585

High

383231

RL26A
Large ribosomal subunit protein uL24A

2

2

High-throughput

0.584

High

383270

RL16A
Large ribosomal subunit protein uL13A

2

2

High-throughput

0.584

High

383344

NOG2
Nucleolar GTP-binding protein 2

2

2

Small-scale

0.584

High

383224

RL25
Large ribosomal subunit protein uL23

2

0

High-throughput

0.559

High

383243

RL31A
Large ribosomal subunit protein eL31A

2

0

High-throughput

0.559

High

383265

SIS1
Protein SIS1

2

0

High-throughput

0.559

High

383267

KRR1
KRR1 small subunit processome component

2

0

Small-scale

0.559

High

383319

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

383272

TF2B
Transcription initiation factor IIB

2

0

High-throughput

0.547

High

383343

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.536

High

383375

MAK21
Ribosome biogenesis protein MAK21

1

1

High-throughput

0.536

High

383261

SKI3
Superkiller protein 3

1

0

High-throughput

0.513

High

383278

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.513

High

383303

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.513

High

383312

ARB1
ABC transporter ATP-binding protein ARB1

1

0

High-throughput

0.513

High

383324

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.513

High

383352

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

383368

BUD20
Bud site selection protein 20

1

0

High-throughput

0.513

High

383380

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.513

High

364202

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.479

High

383029

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.479

High

383225

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.479

High

383226

RLA2
Large ribosomal subunit protein P2A

1

1

High-throughput

0.479

High

383227

RL7A
Large ribosomal subunit protein uL30A

1

2

High-throughput

0.479

High

383228

RL9A
Large ribosomal subunit protein uL6A

1

2

High-throughput

0.479

High

383229

RL6B
Large ribosomal subunit protein eL6B

1

2

High-throughput

0.479

High

383232

RL33A
Large ribosomal subunit protein eL33A

1

1

High-throughput

0.479

High

383233

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.479

High

383234

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

383236

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

3

High-throughput

0.479

High

383237

SC160
Protein SCP160

1

2

High-throughput

0.479

High

383240

IF2B
Eukaryotic translation initiation factor 2 subunit beta

1

1

High-throughput

0.479

High

383242

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

383247

RL2A
Large ribosomal subunit protein uL2A

1

1

High-throughput

0.479

High

383257

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

383260

RL8A
Large ribosomal subunit protein eL8A

1

2

High-throughput

0.479

High

383266

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

383268

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

383269

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.479

High

383273

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

383274

RL8B
Large ribosomal subunit protein eL8B

1

2

High-throughput

0.479

High

383275

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

383279

AFG2
ATPase family gene 2 protein

1

3

High-throughput

0.479

High

383282

MRT4
Ribosome assembly factor MRT4

1

2

Small-scale

0.479

High

383283

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

383284

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

383286

RRP1
Ribosomal RNA-processing protein 1

1

1

Small-scale

0.479

High

383293

GBLP
Small ribosomal subunit protein RACK1

1

8

High-throughput

0.479

High

383294

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.479

High

383295

RDH54
DNA repair and recombination protein RDH54

1

3

High-throughput

0.479

High

383308

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.479

High

383316

RL34B
Large ribosomal subunit protein eL34B

1

1

High-throughput

0.479

High

383320

RLP7
Ribosome biogenesis protein RLP7

1

2

High-throughput

0.479

High

383322

RL33B
Large ribosomal subunit protein eL33B

1

1

High-throughput

0.479

High

383323

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

383333

RL9B
Large ribosomal subunit protein uL6B

1

2

High-throughput

0.479

High

383334

VID30
GID complex subunit 1

1

1

High-throughput

0.479

High

383335

LSG1
Large subunit GTPase 1

1

2

High-throughput

0.479

High

383338

RL26B
Large ribosomal subunit protein uL24B

1

2

High-throughput

0.479

High

383345

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.479

High

383349

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.479

High

383351

RL34A
Large ribosomal subunit protein eL34A

1

1

High-throughput

0.479

High

383354

RL6A
Large ribosomal subunit protein eL6A

1

2

High-throughput

0.479

High

383356

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

383358

HAS1
ATP-dependent RNA helicase HAS1

1

1

High-throughput

0.479

High

383360

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

383361

DHR1
Probable ATP-dependent RNA helicase DHR1

1

3

High-throughput

0.479

High

383365

NOC4
Nucleolar complex protein 4

1

1

High-throughput

0.479

High

383377

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.479

High

383378

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

149451

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

383222

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

383230

RL17A
Large ribosomal subunit protein uL22A

1

0

High-throughput

0.458

High

383235

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

383238

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

383239

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

383241

TBA1
Tubulin alpha-1 chain

1

0

Small-scale

0.458

High

383245

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

383246

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

383249

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

383252

RLA3
Large ribosomal subunit protein P1B

1

0

High-throughput

0.458

High

383254

PDR1
Transcription factor PDR1

1

0

High-throughput

0.458

High

383256

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.458

High

383259

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

383263

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.458

High

383264

RL24B
Large ribosomal subunit protein eL24B

1

0

High-throughput

0.458

High

383271

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

383276

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

383280

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

383281

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

383285

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

383287

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

383291

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.458

High

383297

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.458

High

383299

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

383300

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.458

High

383302

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

383307

CRP1
Cruciform DNA-recognizing protein 1 [Cleaved into: CRP1 short N-terminal subpeptide; CRP1 short C-terminal subpeptide]

1

0

High-throughput

0.458

High

383309

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

383310

ECM1
Shuttling pre-60S factor ECM1

1

0

High-throughput

0.458

High

383311

NOP16
Nucleolar protein 16

1

0

High-throughput

0.458

High

383315

TM108
Protein TMA108

1

0

High-throughput

0.458

High

383317

ULP2
Ubiquitin-like-specific protease 2

1

0

Small-scale

0.458

High

383321

NOP2
25S rRNA

1

0

Small-scale

0.458

High

383327

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

383328

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

383330

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

383331

RL37A
Large ribosomal subunit protein eL37A

1

0

High-throughput

0.458

High

383332

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.458

High

383340

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

383342

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

0

Small-scale

0.458

High

383346

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

Small-scale

0.458

High

383350

RL22B
Large ribosomal subunit protein eL22B

1

0

High-throughput

0.458

High

383353

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

383355

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.458

High

383362

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

383363

LTN1
E3 ubiquitin-protein ligase listerin

1

0

Small-scale

0.458

High

383366

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

383367

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

383369

SGO1
Shugoshin

1

0

High-throughput

0.458

High

383370

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

383373

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

383376

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.458

High

383244

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

3

High-throughput

0.445

High

383251

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

383304

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

383357

GCN5
Histone acetyltransferase GCN5

1

2

High-throughput

0.445

High

383339

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

383262

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.426

High

383289

GPT2
Glycerol-3-phosphate O-acyltransferase 2

1

0

High-throughput

0.426

High

383292

CCL1
Cyclin CCL1

1

0

High-throughput

0.426

High

383336

CGR1
rRNA-processing protein CGR1

1

0

High-throughput

0.426

High

383341

PESC
Pescadillo homolog

1

0

Small-scale

0.426

High

383374

NOP53
Ribosome biogenesis protein NOP53

1

0

Small-scale

0.426

High

383379

CENPI
Inner kinetochore subunit CTF3

1

0

High-throughput

0.426

High

383306

RPF1
Ribosome production factor 1

1

1

High-throughput

0.407

High

383359

TCB3
Tricalbin-3

1

0

High-throughput

0.279

Low

383288

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

383290

RPF2
Ribosome biogenesis protein RPF2

1

0

Small-scale

0.249

Low

383296

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

383298

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.249

Low

383301

YB8A
Putative uncharacterized protein YBR285W

1

0

Small-scale

0.249

Low

383305

SSF1
Ribosome biogenesis protein SSF1

1

0

High-throughput

0.249

Low

383318

SNL1
HSP70 co-chaperone SNL1

1

0

Small-scale

0.249

Low

383325

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

383348

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

383372

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

383381

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

383258

CHS2
Chitin synthase 2

1

0

High-throughput

0.232

Low

383277

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low

383313

PIC2
Mitochondrial phosphate carrier protein 2

1

0

High-throughput

0.232

Low

383314

COX15
Heme A synthase COX15

1

0

High-throughput

0.232

Low

383326

PHO86
Inorganic phosphate transporter PHO86

1

0

High-throughput

0.232

Low

383329

SEC16
COPII coat assembly protein SEC16

1

0

High-throughput

0.232

Low

383337

YG1I
Uncharacterized membrane protein YGR026W

1

0

High-throughput

0.232

Low

383371

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025