Interactor 1: RRP46 (P53256)
Exosome complex component RRP46 (Ribosomal RNA-processing protein 46)
Gene: RRP46
Interactor 2: RRP44 (Q08162)
Exosome complex exonuclease DIS3 (EC 3.1.13.-) (EC 3.1.26.-) (Chromosome disjunction protein 3) (Ribosomal RNA-processing protein 44)
Gene: DIS3
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.983 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12972615, 17942686, 11805826, 16429126, 28877463, 17173052, 18314965, 19879841, 14759368, 24336220, 12837249, 16554755, 27174052, 37968396, 16729021 |
| Identification Methods | coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, pull down, biochemical, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | OB_Dis3~RNase_PH, RNB~RNase_PH, OB_Dis3~RNase_PH_C |
| Common GO terms | GO:0000176 - nuclear exosome (RNase complex) GO:0000177 - cytoplasmic exosome (RNase complex) GO:0000178 - exosome (RNase complex) GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005634 - nucleus and 7 others more... |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
