HitPredict

Interactor 1: COS6 (P53344)
Protein COS6
Gene: COS6

Interactor 2: COS1 (P53822)
Protein COS1
Gene: COS1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000324 - fungal-type vacuole GO:0005768 - endosome GO:0043328 - protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 381 Sc			1 381
+	Sc
		859928 COS6_YEAST (1-381): 0: 534: 100.00		MST27_YEAST (1-175): 2.29e-52: 175: 22.91
+	Sc
		753263 COS8_YEAST (1-380): 0: 518: 81.05		MST28_YEAST (1-175): 2.21e-57: 188: 22.35
+	Sc
		753276 COS8_YEAST (1-380): 0: 518: 81.05		MST27_YEAST (1-175): 2.29e-52: 175: 22.91
+	Sc
		90166 COS8_YEAST (1-380): 0: 518: 81.05		YAJ3_YEAST (54-201): 4.09e-44: 152: 25.17
+	Sc
		762852 PRM8_YEAST (1-186): 1.21e-65: 210: 22.11		PRM9_YEAST (1-186): 6.12e-58: 192: 20.64
+	Sc
		762855 MST28_YEAST (1-175): 2.22e-60: 196: 20.67		MST28_YEAST (1-175): 2.21e-57: 188: 22.35
+	Sc
		762860 MST28_YEAST (1-175): 2.22e-60: 196: 20.67		MST27_YEAST (1-175): 2.29e-52: 175: 22.91
+	Sc
		859926 MST27_YEAST (1-175): 2.39e-56: 186: 22.35		MST27_YEAST (1-175): 2.29e-52: 175: 22.91
+	Sc
		762804 UIP3_YEAST (1-164): 2.74e-50: 170: 20.83		UIP3_YEAST (1-164): 4.29e-50: 169: 22.62
+	Sc
		629917 YCP7_YEAST (1-189): 2.38e-49: 168: 21.54		YCP7_YEAST (1-189): 6.5e-49: 167: 22.56
+	Sc
		762805 UIP3_YEAST (1-164): 2.74e-50: 170: 20.83		KTD1_YEAST (1-161): 3.46e-45: 157: 24.10
+	Sc
		762842 KTD1_YEAST (1-161): 1.87e-49: 168: 23.03		KTD1_YEAST (1-161): 3.46e-45: 157: 24.10
+	Sc
		753292 YHE4_YEAST (90-199): 6.44e-30: 116: 18.46		YHE4_YEAST (98-199): 1.8e-28: 112: 19.01