HitPredict

Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

The method score is based on:

Property	Details
Experiments	12852857, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000132 - establishment of mitotic spindle orientation GO:0000278 - mitotic cell cycle GO:0000776 - kinetochore GO:0000922 - spindle pole GO:0005737 - cytoplasm and 8 others more... GO:0005813 - centrosome GO:0005814 - centriole GO:0005819 - spindle GO:0005829 - cytosol GO:0008017 - microtubule binding GO:0015630 - microtubule cytoskeleton GO:0019901 - protein kinase binding GO:0051081 - nuclear membrane disassembly
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	603
Hs

1	1278

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024