Protein: KLHL8
Kelch-like protein 8

Gene: KLHL8, kel-8
Organism: Caenorhabditis elegans
Interactions: 57
UniProt ID: G5ED84

Gene Ontology (top 5):
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0014069 - postsynaptic density
GO:0016567 - protein ubiquitination
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0043005 - neuron projection

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

105875

CUL3
Cullin-3

1

20

Small-scale

0.713

High

105878

Q18776
BTB domain-containing protein

1

3

High-throughput

0.590

High

105871

PSA3
Proteasome subunit alpha type-3

2

1

High-throughput

0.576

High

105858

PSA1
Proteasome subunit alpha type-1

2

1

High-throughput

0.559

High

105887

PSA2
Proteasome subunit alpha type-2

2

1

High-throughput

0.559

High

105890

PSA7
Proteasome subunit alpha type-7

2

1

High-throughput

0.559

High

105896

Q9U2T9
Intersectin-1

2

4

Small-scale

0.543

High

105891

PSA5
Proteasome subunit alpha type-5

2

1

High-throughput

0.526

High

103407

G4RZC8
PID domain-containing protein

1

6

High-throughput

0.464

High

105851

G5EG39
Skp1-related protein

1

4

High-throughput

0.457

High

105852

H2KZ17
DiSHevelled related

1

10

High-throughput

0.439

High

69953

B1Q240
DiSHevelled related

1

11

High-throughput

0.417

High

105848

G5EDL3
Aurora kinase

1

6

High-throughput

0.417

High

105849

G5EEZ4
WD repeat-containing protein 55

1

4

High-throughput

0.417

High

105850

G5EFD7
WD_REPEATS_REGION domain-containing protein

1

3

High-throughput

0.417

High

105854

CDC37
Probable Hsp90 co-chaperone cdc37

1

1

High-throughput

0.417

High

105864

MPK1
Mitogen-activated protein kinase mpk-1

1

2

High-throughput

0.417

High

105867

U2AF2
Splicing factor U2AF 65 kDa subunit

1

1

High-throughput

0.417

High

105870

RAPSN
43 kDa receptor-associated protein of the synapse homolog

1

3

High-throughput

0.417

High

105872

Q09584
U1 small nuclear ribonucleoprotein 70 kDa

1

2

High-throughput

0.417

High

105877

PMK1
Mitogen-activated protein kinase pmk-1

1

3

High-throughput

0.417

High

105879

MAAI
Probable maleylacetoacetate isomerase

1

3

High-throughput

0.417

High

105881

Q20308
Nicotinamide N-methyltransferase

1

2

High-throughput

0.417

High

105882

MKK4
MAP kinase kinase mkk-4

1

9

High-throughput

0.417

High

105883

Q20660
SHSP domain-containing protein

1

3

High-throughput

0.417

High

105884

MEK1
Dual specificity mitogen-activated protein kinase kinase mek-1

1

7

High-throughput

0.417

High

105893

Q9N4H6
maleylacetoacetate isomerase

1

3

High-throughput

0.417

High

105894

Q9NGT3
HORMA domain-containing protein

1

3

High-throughput

0.417

High

105897

Q9U2Z5
Osteoclast-stimulating factor 1

1

6

High-throughput

0.417

High

105899

Q9XXA2
Calponin homology domain-containing protein

1

1

High-throughput

0.417

High

105900

Q9XXI4
Arrestin C-terminal-like domain-containing protein

1

3

High-throughput

0.417

High

105901

CLA1
Protein clarinet

1

6

High-throughput

0.417

High

105874

ARF12
ADP-ribosylation factor 1-like 2

2

0

Small-scale

0.307

High

105861

PSB1
Proteasome subunit beta type-1

2

0

High-throughput

0.300

High

105866

ATPB
ATP synthase subunit beta, mitochondrial

1

0

Small-scale

0.265

Low

105889

UFSP
Ufm1-specific protease

1

0

Small-scale

0.251

Low

105423

G5ECR7
RNA polymerase II transcription factor SIII p18 subunit

1

0

High-throughput

0.238

Low

105853

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.238

Low

105855

FABP7
Fatty acid-binding protein homolog 7

1

0

High-throughput

0.238

Low

105856

O17066
Snurportin-1

1

0

High-throughput

0.238

Low

105857

RAN
GTP-binding nuclear protein ran-1

1

0

High-throughput

0.238

Low

105859

O44606

1

0

High-throughput

0.238

Low

105860

O44608
3-hydroxyacyl-CoA dehydrogenase

1

0

High-throughput

0.238

Low

105862

YLZ6
Putative esterase F42H10.6

1

0

High-throughput

0.238

Low

105863

TPPC3
Trafficking protein particle complex subunit 3 homolog

1

0

High-throughput

0.238

Low

105865

SMA3
Dwarfin sma-3

1

0

High-throughput

0.238

Low

105868

UFC1
Ubiquitin-fold modifier-conjugating enzyme 1

1

0

High-throughput

0.238

Low

105869

T23O
Tryptophan 2,3-dioxygenase

1

0

High-throughput

0.238

Low

105873

KARG1
Probable arginine kinase F46H5.3

1

0

High-throughput

0.238

Low

105876

GNA1
Glucosamine 6-phosphate N-acetyltransferase

1

0

High-throughput

0.238

Low

105880

RPAB3
Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.238

Low

105885

Q22020
Peroxiredoxin-like 2A

1

0

High-throughput

0.238

Low

105886

WDR4
tRNA

1

0

High-throughput

0.238

Low

105888

Q93716
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.238

Low

105892

Q9N3H9
protein-disulfide reductase

1

0

High-throughput

0.238

Low

105895

Q9U2E4
Beta,beta-carotene 9',10'-oxygenase

1

0

High-throughput

0.238

Low

105898

OTUBL
Ubiquitin thioesterase otubain-like

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024