HitPredict

Interactor 1: NEDD4 (P46934)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Interactor 2: CELR2 (Q9HCU4)
Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3)
Gene: CELSR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37863970
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1319 Hs			1 2923
+	Hs
		861810 NEDD4_HUMAN (1-1319): 0: 1940: 100.00		CELR1_HUMAN (2-806): 1.55e-160: 561: 25.78
+	Hs
		861657 NEDD4_HUMAN (1-1319): 0: 1940: 100.00		FAT4_HUMAN (1881-2201): 2.8e-18: 95.3: 10.98
+	Hs
		861610 NEDD4_HUMAN (1-1319): 0: 1940: 100.00		FAT1_HUMAN (1909-2089): 9.31e-17: 90.3: 9.78
+	Hs
		861696 NEDD4_HUMAN (1-1319): 0: 1940: 100.00		FAT3_HUMAN (1285-1425): 1.45e-15: 86.5: 22.54