Protein: FAT1
Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]

Gene: FAT1
Organism: Homo sapiens
Interactions: 131
UniProt ID: Q14517

Gene Ontology (top 5):
GO:0002088 - lens development in camera-type eye
GO:0003382 - epithelial cell morphogenesis
GO:0003412 - establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis
GO:0005509 - calcium ion binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

663544

CMA1
Chymase

2

16

High-throughput

0.776

High

327003

NXPH2
Neurexophilin-2

3

11

High-throughput

0.770

High

1127613

PSG8
Pregnancy-specific beta-1-glycoprotein 8

2

13

High-throughput

0.726

High

62195

PRS37
Probable inactive serine protease 37

1

20

High-throughput

0.691

High

731845

CEAM8
Cell adhesion molecule CEACAM8

1

13

High-throughput

0.691

High

1127612

DKKL1
Dickkopf-like protein 1

3

8

High-throughput

0.662

High

439732

INSR
Insulin receptor

1

7

High-throughput

0.646

High

962045

RHOA
Transforming protein RhoA

3

13

High-throughput

0.633

High

988367

RAC1
Ras-related C3 botulinum toxin substrate 1

3

13

High-throughput

0.633

High

376390

PDGFB
Platelet-derived growth factor subunit B

2

3

High-throughput

0.628

High

363292

EGFR
Epidermal growth factor receptor

1

10

High-throughput

0.618

High

410845

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

14

High-throughput

0.618

High

463963

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

7

High-throughput

0.618

High

1127605

TMPS4
Transmembrane protease serine 4

1

4

High-throughput

0.618

High

1127609

KLK11
Kallikrein-11

1

13

High-throughput

0.618

High

1127593

CB048
Putative uncharacterized protein C2orf48

3

2

High-throughput

0.609

High

1127596

GML
Glycosyl-phosphatidylinositol-anchored molecule-like protein

2

0

High-throughput

0.602

High

1127589

SPSB4
SPRY domain-containing SOCS box protein 4

2

19

High-throughput

0.601

High

376502

LDLR
Low-density lipoprotein receptor

1

0

High-throughput

0.586

High

1127584

LIPH
Lipase member H

2

0

High-throughput

0.585

High

1113101

CUL3
Cullin-3

2

6

High-throughput

0.584

High

469787

CATG
Cathepsin G

1

16

High-throughput

0.575

High

1127599

SIRPD
Signal-regulatory protein delta

1

3

High-throughput

0.575

High

1127617

KLK5
Kallikrein-5

1

10

High-throughput

0.575

High

1127574

IFNE
Interferon epsilon

2

2

High-throughput

0.574

High

1127586

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

2

High-throughput

0.574

High

531070

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

9

High-throughput

0.571

High

622451

ELK1
ETS domain-containing protein Elk-1

2

1

High-throughput

0.571

High

858655

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

4

High-throughput

0.571

High

1038295

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

4

High-throughput

0.571

High

1051230

KPCZ
Protein kinase C zeta type

2

1

High-throughput

0.571

High

1102321

GRB10
Growth factor receptor-bound protein 10

2

8

High-throughput

0.571

High

1127572

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

1

Small-scale

0.552

High

1127602

XAGE1
X antigen family member 1

2

7

High-throughput

0.549

High

1127606

HOME3
Homer protein homolog 3

1

5

Small-scale

0.536

High

66789

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

6

High-throughput

0.536

High

351826

BY55
CD160 antigen

1

6

High-throughput

0.536

High

366600

RENI
Renin

1

2

High-throughput

0.536

High

616081

LAG3
Lymphocyte activation gene 3 protein

1

4

High-throughput

0.536

High

1101260

SLAF1
Signaling lymphocytic activation molecule

1

16

High-throughput

0.536

High

1104396

ILK
Scaffold protein ILK

1

3

High-throughput

0.536

High

1127560

KS6A2
Ribosomal protein S6 kinase alpha-2

1

1

High-throughput

0.536

High

1127561

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.536

High

1127577

SIR6
NAD-dependent protein deacylase sirtuin-6

1

5

High-throughput

0.536

High

1127614

CCL26
C-C motif chemokine 26

1

5

High-throughput

0.536

High

1127615

DTX4
E3 ubiquitin-protein ligase DTX4

1

2

High-throughput

0.536

High

1127618

HYOU1
Hypoxia up-regulated protein 1

1

1

High-throughput

0.536

High

1127568

SUSD4
Sushi domain-containing protein 4

1

0

High-throughput

0.517

High

634756

GRAH
Granzyme H

1

16

High-throughput

0.514

High

546972

FGF3
Fibroblast growth factor 3

1

0

High-throughput

0.513

High

1127570

LYPD4
Ly6/PLAUR domain-containing protein 4

1

0

High-throughput

0.513

High

507971

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

889423

CLK1
Dual specificity protein kinase CLK1

1

5

High-throughput

0.501

High

896527

VASP
Vasodilator-stimulated phosphoprotein

1

5

Small-scale

0.501

High

1127575

HOME1
Homer protein homolog 1

1

5

Small-scale

0.501

High

1127578

ENAH
Protein enabled homolog

1

8

Small-scale

0.501

High

464960

SP1
Transcription factor Sp1

1

2

High-throughput

0.500

High

1127582

DCNP1
Dendritic cell nuclear protein 1

1

6

High-throughput

0.489

High

1127588

UCN3
Urocortin-3

1

2

High-throughput

0.489

High

1127591

LCFC1
Sperm-egg fusion protein LLCFC1

1

3

High-throughput

0.489

High

320242

SRBS2
Sorbin and SH3 domain-containing protein 2

1

6

Small-scale

0.481

High

1121210

TRI14
Tripartite motif-containing protein 14

1

3

High-throughput

0.481

High

174511

TRI66
Tripartite motif-containing protein 66

1

2

High-throughput

0.479

High

218178

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

231141

AIRE
Autoimmune regulator

1

3

High-throughput

0.479

High

373930

RASN
GTPase NRas

1

11

High-throughput

0.479

High

466252

RHOC
Rho-related GTP-binding protein RhoC

1

13

High-throughput

0.479

High

472061

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.479

High

581048

RAC2
Ras-related C3 botulinum toxin substrate 2

1

12

High-throughput

0.479

High

601289

RHOQ
Rho-related GTP-binding protein RhoQ

1

15

High-throughput

0.479

High

774355

BASI
Basigin

1

3

High-throughput

0.479

High

861610

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

4

Small-scale

0.479

High

953448

RAC3
Ras-related C3 botulinum toxin substrate 3

1

13

High-throughput

0.479

High

955166

CDC42
Cell division control protein 42 homolog

1

14

High-throughput

0.479

High

978008

RHOB
Rho-related GTP-binding protein RhoB

1

14

High-throughput

0.479

High

1015440

RHOG
Rho-related GTP-binding protein RhoG

1

12

High-throughput

0.479

High

1126604

GRB7
Growth factor receptor-bound protein 7

1

9

Small-scale

0.479

High

1127600

RHOJ
Rho-related GTP-binding protein RhoJ

1

15

High-throughput

0.479

High

1127601

RHOF
Rho-related GTP-binding protein RhoF

1

16

High-throughput

0.479

High

1127607

T106B
Transmembrane protein 106B

1

1

High-throughput

0.479

High

1127620

SAR1B
Small COPII coat GTPase SAR1B

1

3

High-throughput

0.479

High

1127573

NOXA1
NADPH oxidase activator 1

1

0

Small-scale

0.460

High

1127598

TRAF4
TNF receptor-associated factor 4

1

0

Small-scale

0.460

High

766194

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.458

High

820790

TACT
T-cell surface protein tactile

1

0

High-throughput

0.458

High

984114

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.458

High

1099672

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

Small-scale

0.458

High

1127563

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.458

High

1127587

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

Small-scale

0.458

High

1127608

HDAC6
Protein deacetylase HDAC6

1

0

Small-scale

0.458

High

1127610

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1127619

NUB1
NEDD8 ultimate buster 1

1

0

Small-scale

0.458

High

388411

B3AT
Band 3 anion transport protein

1

1

High-throughput

0.445

High

480792

LEG1
Galectin-1

1

5

High-throughput

0.445

High

563765

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

859827

RL28
Large ribosomal subunit protein eL28

1

5

High-throughput

0.445

High

906275

GPC3
Glypican-3

1

2

High-throughput

0.445

High

941781

ARL4C
ADP-ribosylation factor-like protein 4C

1

7

High-throughput

0.445

High

1014097

CBX1
Chromobox protein homolog 1

1

9

Small-scale

0.445

High

1105199

S39A6
Zinc transporter ZIP6

1

4

High-throughput

0.445

High

1127569

WDR74
WD repeat-containing protein 74

1

3

High-throughput

0.445

High

1127576

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

1

High-throughput

0.445

High

1127580

ZNT7
Zinc transporter 7

1

2

High-throughput

0.445

High

1127581

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

2

High-throughput

0.445

High

1127583

MOT10
Monocarboxylate transporter 10

1

2

High-throughput

0.445

High

1127590

AURKB
Aurora kinase B

1

2

High-throughput

0.445

High

1127603

FBX6
F-box only protein 6

1

4

High-throughput

0.445

High

1127611

FBX2
F-box only protein 2

1

4

High-throughput

0.445

High

105934

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

889921

VEGFB
Vascular endothelial growth factor B

1

3

High-throughput

0.437

High

1127585

DNS2B
Deoxyribonuclease-2-beta

1

1

High-throughput

0.437

High

1127592

CALR3
Calreticulin-3

1

1

High-throughput

0.437

High

191991

CAN5
Calpain-5

1

0

High-throughput

0.426

High

1127565

INAVA
Innate immunity activator protein

1

0

High-throughput

0.426

High

1127604

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.426

High

169299

LECT2
Leukocyte cell-derived chemotaxin-2

1

1

High-throughput

0.407

High

183646

RT12
Small ribosomal subunit protein uS12m

1

5

High-throughput

0.407

High

1030778

DEF5
Defensin alpha 5

1

1

High-throughput

0.407

High

1127566

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

1

1

High-throughput

0.407

High

1127579

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.407

High

1127616

RT17
Small ribosomal subunit protein uS17m

1

1

High-throughput

0.407

High

1127571

BRNP3
BMP/retinoic acid-inducible neural-specific protein 3

2

0

High-throughput

0.328

High

1127564

DB135
Beta-defensin 135

1

0

High-throughput

0.279

Low

1127594

IL17F
Interleukin-17F

1

0

High-throughput

0.279

Low

1127597

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.279

Low

397600

NU1M
NADH-ubiquinone oxidoreductase chain 1

1

0

Small-scale

0.251

Low

586209

IGLL1
Immunoglobulin lambda-like polypeptide 1

1

0

Small-scale

0.251

Low

1127562

TAZ
Tafazzin

1

0

High-throughput

0.249

Low

1127595

GPHA2
Glycoprotein hormone alpha-2

1

0

High-throughput

0.249

Low

346763

CER1
Cerberus

1

0

High-throughput

0.232

Low

1127567

NTCP5
Sodium/bile acid cotransporter 5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025