Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Interactor 2: CENPU (Q71F23)
Centromere protein U (CENP-U) (Centromere protein of 50 kDa) (CENP-50) (Interphase centromere complex protein 24) (KSHV latent nuclear antigen-interacting protein 1) (MLF1-interacting protein) (Polo-box-interacting protein 1)
Gene: CENPU

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.741

The method score is based on:

Property Details
Experiments 32707033, 19597481, 28514442, 33961781, 21525413, 21454580
Identification Methods affinity chromatography technology, unspecified method, x-ray crystallography, pull down, isothermal titration calorimetry, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0034451 - centriolar satellite
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 603
Hs

1 418
+ Hs
+ Hs

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Last updated: 15 Jul 2024