Protein: MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1 (EC 3.1.3.-) (Myotubularin-related protein 1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95)

Gene: MTMR1
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q13613

Gene Ontology (top 5):
GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006661 - phosphatidylinositol biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1112357

MTMR2
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2

5

19

High-throughput

0.922

High

331750

MTMR5
Myotubularin-related protein 5

4

16

High-throughput

0.895

High

1112371

MTMRD
Myotubularin-related protein 13

3

18

High-throughput

0.867

High

1112380

MTMR9
Myotubularin-related protein 9

1

18

High-throughput

0.691

High

778673

PRS7
26S proteasome regulatory subunit 7

3

1

High-throughput

0.667

High

914413

EFNB2
Ephrin-B2

3

5

High-throughput

0.667

High

1112372

SKAP1
Src kinase-associated phosphoprotein 1

3

3

High-throughput

0.667

High

1112397

TRI10
Tripartite motif-containing protein 10

3

2

High-throughput

0.667

High

871928

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

3

4

High-throughput

0.662

High

1112392

RAB6B
Ras-related protein Rab-6B

3

4

High-throughput

0.662

High

284311

GEMI
Geminin

3

0

High-throughput

0.646

High

597872

LYAM2
E-selectin

2

1

High-throughput

0.628

High

1112373

HAVR2
Hepatitis A virus cellular receptor 2

2

1

High-throughput

0.628

High

1112376

RPGR
X-linked retinitis pigmentosa GTPase regulator

2

1

High-throughput

0.628

High

1112390

LRC4C
Leucine-rich repeat-containing protein 4C

2

1

High-throughput

0.628

High

1112364

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.602

High

391248

FRIL
Ferritin light chain

2

1

High-throughput

0.601

High

977988

RHOB
Rho-related GTP-binding protein RhoB

2

19

High-throughput

0.584

High

1112384

NADAP
Kanadaptin

2

2

High-throughput

0.584

High

1112398

FBW1B
F-box/WD repeat-containing protein 11

2

5

High-throughput

0.571

High

641591

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

19

High-throughput

0.541

High

1034227

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

19

High-throughput

0.541

High

1101723

PTK7
Inactive tyrosine-protein kinase 7

1

14

High-throughput

0.541

High

190358

COPT1
High affinity copper uptake protein 1

1

2

High-throughput

0.536

High

296774

ST1C4
Sulfotransferase 1C4

1

1

High-throughput

0.536

High

370658

FOS
Protein c-Fos

1

1

High-throughput

0.536

High

625365

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.536

High

718394

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.536

High

997699

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.536

High

1022848

EFNB1
Ephrin-B1

1

5

High-throughput

0.536

High

1112362

EFNB3
Ephrin-B3

1

5

High-throughput

0.536

High

1112377

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

1

High-throughput

0.536

High

1112381

FEM1A
Protein fem-1 homolog A

1

1

High-throughput

0.536

High

1112386

DUS16
Dual specificity protein phosphatase 16

1

2

High-throughput

0.536

High

1112401

DCAF1
DDB1- and CUL4-associated factor 1

1

3

High-throughput

0.536

High

1112402

TRI17
E3 ubiquitin-protein ligase TRIM17

1

2

High-throughput

0.536

High

339077

NADK
NAD kinase

1

0

High-throughput

0.513

High

349669

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

1

0

High-throughput

0.513

High

1112382

NAA11
N-alpha-acetyltransferase 11

1

0

High-throughput

0.513

High

1112385

STRA6
Receptor for retinol uptake STRA6

1

0

High-throughput

0.513

High

1112393

BEX4
Protein BEX4

1

0

High-throughput

0.513

High

1112395

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.513

High

1112400

CRYL1
Lambda-crystallin homolog

1

0

High-throughput

0.513

High

1091488

DLG1
Disks large homolog 1

1

5

High-throughput

0.501

High

609875

IBP3
Insulin-like growth factor-binding protein 3

1

1

High-throughput

0.489

High

706119

S10A2
Protein S100-A2

1

6

High-throughput

0.489

High

1112399

PNMA2
Paraneoplastic antigen Ma2

1

1

High-throughput

0.489

High

126583

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

373917

RASN
GTPase NRas

1

14

High-throughput

0.479

High

374579

RASH
GTPase HRas

1

10

High-throughput

0.479

High

375497

RASK
GTPase KRas

1

13

High-throughput

0.479

High

540442

LAMP1
Lysosome-associated membrane glycoprotein 1

1

1

High-throughput

0.479

High

581032

RAC2
Ras-related C3 botulinum toxin substrate 2

1

15

High-throughput

0.479

High

582780

EZRI
Ezrin

1

2

High-throughput

0.479

High

601278

RHOQ
Rho-related GTP-binding protein RhoQ

1

19

High-throughput

0.479

High

710229

EPHA2
Ephrin type-A receptor 2

1

4

High-throughput

0.479

High

715575

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

904687

MECP2
Methyl-CpG-binding protein 2

1

2

High-throughput

0.479

High

910039

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

952803

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.479

High

953433

RAC3
Ras-related C3 botulinum toxin substrate 3

1

17

High-throughput

0.479

High

955142

CDC42
Cell division control protein 42 homolog

1

19

High-throughput

0.479

High

962026

RHOA
Transforming protein RhoA

1

17

High-throughput

0.479

High

962735

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

988347

RAC1
Ras-related C3 botulinum toxin substrate 1

1

17

High-throughput

0.479

High

1004052

CXAR
Coxsackievirus and adenovirus receptor

1

1

High-throughput

0.479

High

1015422

RHOG
Rho-related GTP-binding protein RhoG

1

15

High-throughput

0.479

High

1112359

RAB35
Ras-related protein Rab-35

1

6

High-throughput

0.479

High

1112360

KS6A2
Ribosomal protein S6 kinase alpha-2

1

3

High-throughput

0.479

High

1112361

RHOH
Rho-related GTP-binding protein RhoH

1

19

High-throughput

0.479

High

1112368

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1112369

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1112370

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

High-throughput

0.479

High

1112375

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1112379

AURKB
Aurora kinase B

1

5

High-throughput

0.479

High

1112383

CP250
Centrosome-associated protein CEP250

1

2

High-throughput

0.479

High

1112387

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.479

High

1112388

RHOJ
Rho-related GTP-binding protein RhoJ

1

19

High-throughput

0.479

High

1112389

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1112396

ZO2
Tight junction protein 2

1

6

High-throughput

0.479

High

463509

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.458

High

642855

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

938562

PSA
Puromycin-sensitive aminopeptidase

1

0

High-throughput

0.458

High

1041050

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1112358

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1112365

EAPP
E2F-associated phosphoprotein

1

0

High-throughput

0.458

High

1112374

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1112378

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.458

High

1112391

CASS4
Cas scaffolding protein family member 4

1

1

High-throughput

0.457

High

58815

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

4

High-throughput

0.445

High

239056

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.445

High

516759

SCHI1
Schwannomin-interacting protein 1

1

1

High-throughput

0.445

High

529759

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

105890

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

211639

ZNHI1
Zinc finger HIT domain-containing protein 1

1

1

High-throughput

0.437

High

695401

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

964925

WDR5
WD repeat-containing protein 5

1

3

Small-scale

0.437

High

1112363

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

1

High-throughput

0.407

High

538304

LIPC
Hepatic triacylglycerol lipase

2

0

High-throughput

0.328

High

224481

PI15
Peptidase inhibitor 15

1

0

High-throughput

0.279

Low

353936

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

0

High-throughput

0.279

Low

1112366

IGFL3
Insulin growth factor-like family member 3

1

0

High-throughput

0.279

Low

1112367

PKHG7
Pleckstrin homology domain-containing family G member 7

1

0

High-throughput

0.232

Low

1112394

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025