Interactor 1: DAPK1 (P53355)
Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)
Gene: DAPK1

Interactor 2: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 0.55 0.593

The method score is based on:

Property Details
Experiments 19180116
Identification Methods enzymatic study, pull down, affinity chromatography technology, protein kinase assay, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0010506 - regulation of autophagy
GO:0010508 - positive regulation of autophagy
GO:0043066 - negative regulation of apoptotic process
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024