HitPredict

Interactor 1: CEBPG (P53567)
CCAAT/enhancer-binding protein gamma (C/EBP gamma)
Gene: CEBPG

Interactor 2: AF17 (P55198)
Protein AF-17 (ALL1-fused gene from chromosome 17 protein)
Gene: MLLT6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	16189514, 28514442, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 150 Hs			1 1093
+	Hs
		568255 ATF7_HUMAN (12-148): 2.95e-35: 129: 25.18		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		876591 CREB5_HUMAN (13-141): 7.21e-32: 119: 20.77		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		547760 ATF2_HUMAN (6-150): 9.25e-30: 114: 25.17		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		876601 CEBPE_HUMAN (13-137): 2.1e-29: 109: 31.01		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		831146 CEBPA_HUMAN (22-137): 9.61e-27: 104: 33.33		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		401708 JUN_HUMAN (18-128): 1.62e-23: 95.2: 20.72		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		345553 FOS_HUMAN (1-131): 4.45e-24: 97.6: 21.53		JADE2_HUMAN (3-608): 2.62e-66: 241: 20.95
+	Hs
		299037 CEBPB_HUMAN (36-136): 3.85e-30: 112: 42.16		PHF14_HUMAN (7-320): 1.35e-60: 226: 25.08
+	Hs
		554262 CEBPB_HUMAN (36-136): 3.85e-30: 112: 42.16		MUC1_HUMAN (314-1082): 1.9e-41: 168: 13.53
+	Hs
		401362 JUN_HUMAN (18-128): 1.62e-23: 95.2: 20.72		MUC1_HUMAN (314-1082): 1.9e-41: 168: 13.53