HitPredict

Interactor 1: CLIP3 (B9EHT4)
CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59)
Gene: CLIP3

Interactor 2: AKT1 (P31750)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (AKT1 kinase) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha) (Thymoma viral proto-oncogene)
Gene: AKT1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	19139280
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Pkinase
Common GO terms	GO:0005886 - plasma membrane GO:1903078 - positive regulation of protein localization to plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 547 Mm			1 480
+	Hs
		728376 CLIP3_HUMAN (1-547): 0: 827: 98.54		AKT1_HUMAN (1-480): 0: 600: 98.33
+	Hs
		728611 CLIP3_HUMAN (1-547): 0: 827: 98.54		AKT2_HUMAN (1-477): 0: 570: 81.84
+	Mm
		86293 CLIP3_MOUSE (1-547): 0: 825: 100.00		AKT2_MOUSE (1-477): 0: 567: 82.05
+	Hs
		728438 CYLD_HUMAN (220-529): 8.41e-64: 226: 18.15		AKT1_HUMAN (1-480): 0: 600: 98.33
+	Hs
		728227 DCTN1_HUMAN (409-520): 1.37e-29: 126: 36.21		AKT1_HUMAN (1-480): 0: 600: 98.33
+	Hs
		728258 TBCE_HUMAN (418-491): 2.25e-18: 90.2: 35.53		AKT1_HUMAN (1-480): 0: 600: 98.33
+	Hs
		1051294 TBCB_HUMAN (240-363): 6.96e-31: 122: 29.84		KPCZ_HUMAN (12-477): 7.35e-150: 441: 33.81
+	Hs
		720972 CLIP1_HUMAN (390-524): 9.17e-25: 111: 31.85		KS6A3_HUMAN (36-456): 8.62e-104: 327: 21.82