HitPredict

Interactor 1: TTC3 (P53804)
E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)
Gene: TTC3

Interactor 2: DC2L1 (Q8TCX1)
Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain)
Gene: DYNC2LI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2025 Hs			1 351
+	Hs
		1051377 DCTN1_HUMAN (1227-1708): 2.17e-62: 237: 13.50		DC2L1_HUMAN (1-351): 6.91e-165: 465: 100.00
+	Hs
		198260 DCTN1_HUMAN (1227-1708): 2.17e-62: 237: 13.50		DC1L2_HUMAN (4-315): 1.38e-128: 378: 19.02
+	Hs
		1051535 DCTN1_HUMAN (1227-1708): 2.17e-62: 237: 13.50		DC1L1_HUMAN (4-303): 1.63e-119: 356: 19.38
+	Hs
		174460 OGT1_HUMAN (81-443): 8.81e-20: 98.9: 10.24		DC1L2_HUMAN (4-315): 1.38e-128: 378: 19.02
+	Hs
		685150 STIP1_HUMAN (74-510): 1.57e-24: 112: 13.23		DC1L1_HUMAN (4-303): 1.63e-119: 356: 19.38
+	Hs
		175334 OGT1_HUMAN (81-443): 8.81e-20: 98.9: 10.24		DC1L1_HUMAN (4-303): 1.63e-119: 356: 19.38