Protein: T3JAM
TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3)

Gene: T3JAM, TRAF3IP3
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q9Y228

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005765 - lysosomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

994422

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

3

8

High-throughput

0.675

High

1217371

STRP1
Striatin-interacting protein 1

3

3

High-throughput

0.675

High

1414407

PDC10
Programmed cell death protein 10

3

1

High-throughput

0.675

High

1448656

STRN4
Striatin-4

3

18

High-throughput

0.675

High

1490450

PHOCN
MOB-like protein phocein

3

2

High-throughput

0.675

High

1092947

STRN3
Striatin-3

3

20

High-throughput

0.671

High

1411938

SIKE1
Suppressor of IKBKE 1

3

7

High-throughput

0.671

High

1095010

TRAF3
TNF receptor-associated factor 3

3

14

Small-scale

0.656

High

895163

EMD
Emerin

4

1

High-throughput

0.647

High

1379891

FATE1
Fetal and adult testis-expressed transcript protein

3

0

High-throughput

0.646

High

659319

SP100
Nuclear autoantigen Sp-100

4

9

High-throughput

0.637

High

718049

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

6

High-throughput

0.628

High

1329456

KASH5
Protein KASH5

3

18

High-throughput

0.616

High

1428221

NDEL1
Nuclear distribution protein nudE-like 1

3

19

High-throughput

0.616

High

228650

STRN
Striatin

3

20

High-throughput

0.616

High

1450662

FGOP2
FGFR1 oncogene partner 2

3

6

High-throughput

0.616

High

1461658

STRP2
Striatin-interacting protein 2

3

3

High-throughput

0.616

High

140035

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

2

1

High-throughput

0.606

High

850860

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

3

High-throughput

0.606

High

1087346

STX4
Syntaxin-4

2

7

High-throughput

0.606

High

1159660

STX1A
Syntaxin-1A

2

7

High-throughput

0.606

High

1228221

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

2

2

High-throughput

0.606

High

1308082

GRM2A
GRAM domain-containing protein 2A

2

2

High-throughput

0.606

High

1430099

RGAP1
Rac GTPase-activating protein 1

2

4

High-throughput

0.606

High

718197

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

3

6

High-throughput

0.604

High

1454421

STK26
Serine/threonine-protein kinase 26

3

20

High-throughput

0.604

High

1227724

A16L1
Autophagy-related protein 16-1

3

15

Small-scale

0.599

High

275131

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

2

0

High-throughput

0.580

High

761173

EVI2B
Protein EVI2B

2

0

High-throughput

0.580

High

1204205

RIPL1
RILP-like protein 1

2

0

High-throughput

0.580

High

1279104

RIC3
Protein RIC-3

2

0

High-throughput

0.580

High

1281209

CPLX4
Complexin-4

2

0

High-throughput

0.580

High

1324734

CBARP
Voltage-dependent calcium channel beta subunit-associated regulatory protein

2

0

High-throughput

0.580

High

1429148

MFF
Mitochondrial fission factor

2

0

High-throughput

0.580

High

1433836

OSBL3
Oxysterol-binding protein-related protein 3

2

0

High-throughput

0.580

High

1462611

MNAR1
Major intrinsically disordered Notch2-binding receptor 1

2

0

High-throughput

0.580

High

161654

RGPD8
RANBP2-like and GRIP domain-containing protein 8

2

7

High-throughput

0.574

High

890617

RBP2
E3 SUMO-protein ligase RanBP2

2

8

High-throughput

0.574

High

1406305

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

2

7

High-throughput

0.574

High

1458249

TFP11
Tuftelin-interacting protein 11

2

2

High-throughput

0.573

High

220819

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

1

7

High-throughput

0.573

High

1446847

TRI36
E3 ubiquitin-protein ligase TRIM36

1

16

High-throughput

0.573

High

1278149

MAVS
Mitochondrial antiviral-signaling protein

1

5

Small-scale

0.561

High

64561

CC88B
Coiled-coil domain-containing protein 88B

2

17

High-throughput

0.553

High

65189

GG6L9
Golgin subfamily A member 6-like protein 9

2

20

High-throughput

0.553

High

666933

CCNC
Cyclin-C

2

3

High-throughput

0.553

High

1260695

CEP68
Centrosomal protein of 68 kDa

2

9

High-throughput

0.553

High

1277657

K1C27
Keratin, type I cytoskeletal 27

2

9

High-throughput

0.553

High

1395264

LMBL3
Lethal(3)malignant brain tumor-like protein 3

2

3

High-throughput

0.553

High

1430841

STMN4
Stathmin-4

2

1

High-throughput

0.553

High

1459344

ZRAN1
Ubiquitin thioesterase ZRANB1

2

11

High-throughput

0.553

High

991773

DYL1
Dynein light chain 1, cytoplasmic

1

4

High-throughput

0.536

High

1459838

TBK1
Serine/threonine-protein kinase TBK1

1

20

Small-scale

0.536

High

239252

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.523

High

1413302

WAC
WW domain-containing adapter protein with coiled-coil

1

4

High-throughput

0.523

High

605853

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

10

High-throughput

0.515

High

789043

TGFR2
TGF-beta receptor type-2

1

1

High-throughput

0.515

High

853438

CBX5
Chromobox protein homolog 5

1

5

High-throughput

0.515

High

947381

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

8

Small-scale

0.506

High

610945

TCPA
T-complex protein 1 subunit alpha

1

10

High-throughput

0.489

High

832839

BCL6
B-cell lymphoma 6 protein

1

3

Small-scale

0.489

High

876228

TCPE
T-complex protein 1 subunit epsilon

1

13

High-throughput

0.489

High

899286

TCPQ
T-complex protein 1 subunit theta

1

16

High-throughput

0.489

High

999430

HBB
Hemoglobin subunit beta

1

3

High-throughput

0.489

High

999705

HBA
Hemoglobin subunit alpha

1

3

High-throughput

0.489

High

1293837

FBX11
F-box only protein 11

1

2

High-throughput

0.489

High

1326462

MINK1
Misshapen-like kinase 1

1

20

High-throughput

0.489

High

1490451

STK24
Serine/threonine-protein kinase 24

1

20

High-throughput

0.489

High

931621

RD23A
UV excision repair protein RAD23 homolog A

1

3

High-throughput

0.470

High

1395371

CC136
Coiled-coil domain-containing protein 136

1

18

High-throughput

0.439

High

173571

XPO1
Exportin-1

1

8

Small-scale

0.437

High

775622

NU214
Nuclear pore complex protein Nup214

1

9

Small-scale

0.437

High

854956

RECQ1
ATP-dependent DNA helicase Q1

1

6

High-throughput

0.437

High

1461750

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

7

High-throughput

0.437

High

138890

STK25
Serine/threonine-protein kinase 25

1

20

High-throughput

0.407

High

882220

TCPG
T-complex protein 1 subunit gamma

1

12

High-throughput

0.407

High

343711

GGPPS
Geranylgeranyl pyrophosphate synthase

2

0

High-throughput

0.328

High

1199160

PKHO1
Pleckstrin homology domain-containing family O member 1

2

0

High-throughput

0.316

High

1207654

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1214433

GORAB
RAB6-interacting golgin

2

0

High-throughput

0.316

High

1308354

TM139
Transmembrane protein 139

2

0

High-throughput

0.316

High

1324886

LRC25
Leucine-rich repeat-containing protein 25

2

0

High-throughput

0.316

High

1340386

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.316

High

1397849

CC138
Coiled-coil domain-containing protein 138

2

0

High-throughput

0.316

High

1433039

LIME1
Lck-interacting transmembrane adapter 1

2

0

High-throughput

0.316

High

1392139

CDA7L
Cell division cycle-associated 7-like protein

1

0

High-throughput

0.299

High

351767

SG1D2
Secretoglobin family 1D member 2

1

0

High-throughput

0.279

Low

1242400

GOLM2
Protein GOLM2

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025