HitPredict

Interactor 1: MSS4 (P47224)
Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)
Gene: RABIF

Interactor 2: RAB8B (Q92930)
Ras-related protein Rab-8B (EC 3.6.5.2)
Gene: RAB8B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.80	0.765

Property	Details
Experiments	33961781, 28514442, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Mss4~Ras
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 123 Hs			1 207
+	Hs
		866372 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB10_HUMAN (1-197): 1.11e-94: 276: 70.20
+	Hs
		866373 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB1A_HUMAN (1-204): 2.29e-90: 265: 52.94
+	Mm
		981414 MSS4_MOUSE (1-123): 1.16e-71: 211: 93.50		RAB1A_MOUSE (1-204): 2.29e-90: 265: 52.94
+	Hs
		866394 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB1B_HUMAN (1-204): 3.85e-90: 264: 51.96
+	Hs
		866368 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB13_HUMAN (1-206): 2.08e-89: 262: 64.08
+	Hs
		866371 MSS4_HUMAN (1-123): 1.16e-71: 211: 100.00		RAB8A_HUMAN (1-207): 1.4e-88: 260: 82.61
+	Dm
		194907 MSS4_DROME (13-123): 3.16e-52: 162: 39.29		O15971_DROME (3-181): 4.73e-90: 264: 74.30
+	Dm
		197420 MSS4_DROME (13-123): 3.16e-52: 162: 39.29		O18338_DROME (1-207): 7.44e-87: 256: 78.74
+	Dm
		197103 MSS4_DROME (13-123): 3.16e-52: 162: 39.29		O18332_DROME (1-204): 4.19e-86: 254: 53.37