Protein: MSS4
Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)

Gene: MSS4, RABIF
Organism: Homo sapiens
Interactions: 62
UniProt ID: P47224

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0006892 - post-Golgi vesicle-mediated transport
GO:0007264 - small GTPase-mediated signal transduction
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

630405

RAB3A
Ras-related protein Rab-3A

5

13

Small-scale

0.934

High

866394

RAB1B
Ras-related protein Rab-1B

5

8

High-throughput

0.931

High

866371

RAB8A
Ras-related protein Rab-8A

5

9

Small-scale

0.922

High

866372

RAB10
Ras-related protein Rab-10

4

9

Small-scale

0.896

High

866373

RAB1A
Ras-related protein Rab-1A

4

6

Small-scale

0.895

High

630469

RAB3B
Ras-related protein Rab-3B

3

12

High-throughput

0.858

High

866368

RAB13
Ras-related protein Rab-13

2

9

High-throughput

0.811

High

343172

RAB3D
Ras-related protein Rab-3D

2

13

High-throughput

0.783

High

866389

RAB3C
Ras-related protein Rab-3C

2

13

High-throughput

0.783

High

866388

RAB8B
Ras-related protein Rab-8B

3

9

High-throughput

0.765

High

62182

RAB19
Ras-related protein Rab-19

2

8

High-throughput

0.700

High

866374

RAP1A
Ras-related protein Rap-1A

1

4

High-throughput

0.691

High

866370

RAB15
Ras-related protein Rab-15

1

11

Small-scale

0.621

High

866386

RASF5
Ras association domain-containing protein 5

2

0

High-throughput

0.606

High

131356

EIF3F
Eukaryotic translation initiation factor 3 subunit F

2

0

High-throughput

0.580

High

866379

LAR1B
La-related protein 1B

2

0

High-throughput

0.580

High

866385

LNX1
E3 ubiquitin-protein ligase LNX

2

0

High-throughput

0.580

High

866399

LMCD1
LIM and cysteine-rich domains protein 1

2

0

High-throughput

0.580

High

866391

KIFC3
Kinesin-like protein KIFC3

2

1

High-throughput

0.553

High

866376

REL
Proto-oncogene c-Rel

1

0

High-throughput

0.549

High

862741

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

High-throughput

0.536

High

866377

IQGA2
Ras GTPase-activating-like protein IQGAP2

1

1

High-throughput

0.536

High

866401

ZN148
Zinc finger protein 148

1

1

High-throughput

0.536

High

219141

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.518

High

866392

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

High-throughput

0.518

High

238430

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.513

High

557170

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.513

High

569172

CD59
CD59 glycoprotein

1

0

High-throughput

0.513

High

580742

PVR
Poliovirus receptor

1

0

High-throughput

0.513

High

669260

PTAFR
Platelet-activating factor receptor

1

0

High-throughput

0.513

High

854792

RECQ1
ATP-dependent DNA helicase Q1

1

0

High-throughput

0.513

High

866384

WDR48
WD repeat-containing protein 48

1

0

High-throughput

0.513

High

866387

CELF1
CUGBP Elav-like family member 1

1

0

High-throughput

0.513

High

866390

SNAG
Gamma-soluble NSF attachment protein

1

0

High-throughput

0.513

High

866393

ADT4
ADP/ATP translocase 4

1

0

High-throughput

0.513

High

866400

CAH14
Carbonic anhydrase 14

1

0

High-throughput

0.513

High

866380

ZN544
Zinc finger protein 544

1

0

High-throughput

0.486

High

714

A0A087WWI0
Leucine-rich melanocyte differentiation-associated protein

1

1

High-throughput

0.470

High

866383

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

473674

ITA5
Integrin alpha-5

1

3

Small-scale

0.439

High

603759

ITA2
Integrin alpha-2

1

3

Small-scale

0.439

High

654942

ITA6
Integrin alpha-6

1

3

Small-scale

0.439

High

683587

ITA3
Integrin alpha-3

1

3

Small-scale

0.439

High

866395

LRMDA
Leucine-rich melanocyte differentiation-associated protein

1

1

High-throughput

0.439

High

352693

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.426

High

538828

GTR3
Solute carrier family 2, facilitated glucose transporter member 3

1

0

High-throughput

0.426

High

574166

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.426

High

788593

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.426

High

866382

LHPL4
LHFPL tetraspan subfamily member 4 protein

2

0

High-throughput

0.328

High

866402

LZTS1
Leucine zipper putative tumor suppressor 1

2

0

High-throughput

0.316

High

866398

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.299

High

587023

ITF2
Transcription factor 4

1

0

High-throughput

0.299

High

866381

KAT3
Kynurenine--oxoglutarate transaminase 3

1

0

High-throughput

0.282

High

329235

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.279

Low

640371

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

0

High-throughput

0.279

Low

690468

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.279

Low

866369

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.279

Low

866375

MMSA
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

1

0

High-throughput

0.279

Low

866378

CEA21
Cell adhesion molecule CEACAM21

1

0

High-throughput

0.279

Low

866396

SPE39
Spermatogenesis-defective protein 39 homolog

1

0

High-throughput

0.279

Low

866397

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

0

High-throughput

0.279

Low

471787

RU2B
U2 small nuclear ribonucleoprotein B''

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025