Interactor 1: CAPZB (P47756)
F-actin-capping protein subunit beta (CapZ beta)
Gene: CAPZB
Interactor 2: TWF2 (Q6IBS0)
Twinfilin-2 (A6-related protein) (hA6RP) (Protein tyrosine kinase 9-like) (Twinfilin-1-like protein)
Gene: TWF2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.68 | 1.00 | 0.830 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17353931, 35271311, unassigned3799 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cofilin_ADF~F_actin_cap_B |
| Common GO terms | GO:0030027 - lamellipodium GO:0045296 - cadherin binding GO:0051016 - barbed-end actin filament capping GO:0070062 - extracellular exosome |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
