Interactor 1: ATX3 (P54252)
Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein)
Gene: ATXN3

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 25158237
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0031625 - ubiquitin protein ligase binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 361
Hs

1 440
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024