Interactor 1: ATX3 (P54252)
Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein)
Gene: ATXN3

Interactor 2: OTUB2 (Q96DC9)
Ubiquitin thioesterase OTUB2 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB2) (OTU domain-containing ubiquitin aldehyde-binding protein 2) (Otubain-2) (Ubiquitin-specific-processing protease OTUB2)
Gene: OTUB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 0.55 0.585

The method score is based on:

Property Details
Experiments 19615732, 32814053
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0070536 - protein K63-linked deubiquitination
GO:0071108 - protein K48-linked deubiquitination
Homologous interactions 0

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Last updated: 15 Jul 2024