HitPredict

Interactor 1: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Interactor 2: TBL1R (Q9BZK7)
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)
Gene: TBL1XR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25959826, 32814053
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 815 Hs			1 514
+	Hs
		282866 ATX1_HUMAN (1-815): 0: 1349: 100.00		CIAO1_HUMAN (169-472): 3.95e-22: 99.4: 27.94
+	Hs
		868669 ATX1_HUMAN (1-815): 0: 1349: 100.00		SNR40_HUMAN (50-195): 7.63e-12: 68.7: 11.92
+	Hs
		473550 ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15		SNR40_HUMAN (50-195): 7.63e-12: 68.7: 11.92