HitPredict

Interactor 1: TERF1 (P54274)
Telomeric repeat-binding factor 1 (NIMA-interacting protein 2) (TTAGGG repeat-binding factor 1) (Telomeric protein Pin2/TRF1)
Gene: TERF1

Interactor 2: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.690

The method score is based on:

Property Details
Experiments 11375976, 18160036, 15314656
Identification Methods affinity chromatography technology, enzymatic study, pull down, anti bait coimmunoprecipitation, in-gel kinase assay
Interaction Type physical association, direct interaction, enzymatic reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000723 - telomere maintenance
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 3 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 439
Hs

1 3056
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024