HitPredict

Interactor 1: VATE (P54611)
V-type proton ATPase subunit E (V-ATPase subunit E) (V-ATPase 26 kDa subunit) (Vacuolar proton pump subunit E)
Gene: Vha26

Interactor 2: VATC (Q9V7N5)
V-type proton ATPase subunit C (V-ATPase subunit C) (Vacuolar proton pump subunit C)
Gene: Vha44

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	V-ATPase_C~vATP-synt_E
Common GO terms	GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain GO:0033181 - plasma membrane proton-transporting V-type ATPase complex GO:0046961 - proton-transporting ATPase activity, rotational mechanism GO:1902600 - proton transmembrane transport
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 226 Dm			1 836
+	Sc
		605411 VATE_YEAST (2-226): 3.99e-76: 230: 34.36		VATC_YEAST (540-828): 4.71e-134: 406: 38.57
+	Hs
		597723 VATE1_HUMAN (1-226): 3.25e-100: 291: 63.27		VATC1_HUMAN (2-95): 1.55e-41: 158: 61.70
+	Hs
		736120 VATE1_HUMAN (1-226): 3.25e-100: 291: 63.27		VATC2_HUMAN (2-95): 5.88e-39: 152: 58.51
+	Hs
		1243713 VATE2_HUMAN (1-225): 7.14e-90: 265: 60.89		VATC2_HUMAN (2-95): 5.88e-39: 152: 58.51