HitPredict

Interactor 1: HSP72 (P54652)
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) (Heat shock protein family A member 2)
Gene: HSPA2

Interactor 2: Q96BE0 (Q96BE0)
Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)
Gene: Q96BE0

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HSP70~HSP70
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0140662 - ATP-dependent protein folding chaperone
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 269
+	Hs
		503752 HSP72_HUMAN (1-639): 0: 955: 100.00		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		503543 HS71L_HUMAN (2-639): 0: 953: 81.90		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		503315 HSP7C_HUMAN (3-616): 0: 946: 87.95		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Mm
		926115 HSP7C_MOUSE (3-616): 0: 946: 87.79		HSP7C_MOUSE (1-269): 1.33e-130: 385: 99.63
+	Hs
		871516 HSP72_HUMAN (1-639): 0: 955: 100.00		HSP72_HUMAN (1-269): 1.82e-126: 374: 78.07
+	Hs
		564046 HSP72_HUMAN (1-639): 0: 955: 100.00		HSP76_HUMAN (1-269): 5.75e-126: 373: 69.15
+	Hs
		871593 HSP72_HUMAN (1-639): 0: 955: 100.00		Q53FC7_HUMAN (1-269): 5.5e-126: 373: 68.77
+	Mm
		571859 HS71B_MOUSE (3-639): 0: 942: 82.58		HS71A_MOUSE (1-269): 1.94e-129: 382: 76.95
+	Hs
		503389 HSP7C_HUMAN (3-616): 0: 946: 87.95		HSP76_HUMAN (1-269): 5.75e-126: 373: 69.15
+	Mm
		565418 HSP72_MOUSE (1-639): 0: 946: 97.97		HSP72_MOUSE (1-235): 1.39e-125: 372: 84.26