HitPredict

Interactor 1: RD23A (P54725)
UV excision repair protein RAD23 homolog A (HR23A) (hHR23A)
Gene: RAD23A

Interactor 2: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.834

Property	Details
Experiments	30659753, 33665565
Identification Methods	pull down, unspecified method, affinity chromatography technology, phage display
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 363 Hs			1 81
+	Hs
		872136 RD23A_HUMAN (1-363): 4.01e-119: 350: 100.00		RS27A_HUMAN (1-77): 6.66e-37: 122: 57.14
+	Hs
		872137 RD23A_HUMAN (1-363): 4.01e-119: 350: 100.00		RL40_HUMAN (1-76): 3.79e-33: 112: 57.90
+	Hs
		474969 RD23B_HUMAN (3-363): 1.37e-106: 320: 54.03		UBB_HUMAN (1-76): 2.4e-30: 107: 57.90
+	Dm
		547941 Q9V3W9_DROME (3-362): 9.91e-87: 269: 38.43		RS27A_DROME (1-77): 3.39e-36: 121: 57.14
+	Sp
		251961 RHP23_SCHPO (3-363): 2.02e-78: 247: 33.25		RL402_SCHPO (1-76): 6.88e-32: 109: 55.26
+	Sp
		251959 RHP23_SCHPO (3-363): 2.02e-78: 247: 33.25		RS27A_SCHPO (1-71): 1.02e-29: 104: 53.52
+	Sc
		477610 RAD23_YEAST (3-361): 1e-75: 240: 28.57		RL40A_YEAST (1-76): 1.87e-32: 110: 55.26
+	Pf
		1181547 Q8IJS8_PLAF7 (3-362): 2.53e-72: 232: 24.37		Q7KQK2_PLAF7 (1-76): 5.8e-29: 107: 59.21
+	Dm
		547946 Q9VCD5_DROME (3-362): 3.96e-58: 191: 27.90		RS27A_DROME (1-77): 3.39e-36: 121: 57.14
+	Dm
		1362825 Q9VCD5_DROME (3-362): 3.96e-58: 191: 27.90		NEDD8_DROME (1-76): 2.21e-34: 113: 93.42
+	Dm
		574854 Q9VCD5_DROME (3-362): 3.96e-58: 191: 27.90		RL40_DROME (1-76): 1.76e-33: 112: 57.90
+	Hs
		924216 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		RS27A_HUMAN (1-77): 6.66e-37: 122: 57.14
+	Hs
		924208 UBQL2_HUMAN (2-312): 1.85e-45: 166: 16.08		RS27A_HUMAN (1-77): 6.66e-37: 122: 57.14
+	Hs
		924435 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		RL40_HUMAN (1-76): 3.79e-33: 112: 57.90
+	Hs
		1137416 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		Q5U5U6_HUMAN (1-76): 2.4e-30: 107: 57.90
+	Hs
		1286323 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		Q96C32_HUMAN (1-76): 2.04e-29: 107: 57.90
+	Hs
		475241 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		UBB_HUMAN (1-76): 2.4e-30: 107: 57.90
+	Hs
		924430 UBQL2_HUMAN (2-312): 1.85e-45: 166: 16.08		RL40_HUMAN (1-76): 3.79e-33: 112: 57.90
+	Hs
		1079632 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Hs
		475223 UBQL2_HUMAN (2-312): 1.85e-45: 166: 16.08		UBB_HUMAN (1-76): 2.4e-30: 107: 57.90