HitPredict

Interactor 1: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Interactor 2: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	28514442, 33961781, 27114451
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043130 - ubiquitin binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 409 Hs			1 399
+	Dm
		1375389 Q9VXF9_DROME (1-406): 8.36e-58: 197: 15.39		Q9VXF9_DROME (5-395): 2.61e-124: 368: 46.38
+	Hs
		872317 RD23B_HUMAN (1-409): 1.31e-125: 370: 100.00		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Zm
		80385 B6TNT9_MAIZE (2-406): 5.59e-58: 199: 14.18		K7UR93_MAIZE (5-384): 2.9e-111: 333: 35.25
+	Sc
		697088 RAD23_YEAST (1-407): 2.12e-72: 233: 28.41		DDI1_YEAST (3-395): 7.99e-93: 287: 30.92
+	Hs
		872124 RD23B_HUMAN (1-409): 1.31e-125: 370: 100.00		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Hs
		872229 RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		872226 RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		872222 RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Hs
		872123 RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Hs
		1357342 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		1355403 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		1345051 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Sp
		251965 RHP23_SCHPO (1-409): 1.78e-77: 245: 34.43		DSK2_SCHPO (10-179): 8.15e-29: 117: 17.87
+	Hs
		872136 RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06
+	Sc
		697098 RAD23_YEAST (1-407): 2.12e-72: 233: 28.41		DSK2_YEAST (19-213): 6.83e-31: 123: 15.49
+	Sc
		697061 RAD23_YEAST (1-407): 2.12e-72: 233: 28.41		RAD23_YEAST (5-202): 3.88e-26: 110: 16.00
+	Dm
		1362834 Q9VXF9_DROME (1-406): 8.36e-58: 197: 15.39		Q9VCD5_DROME (5-227): 2.18e-35: 133: 12.88
+	Hs
		803807 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		BAG6_HUMAN (4-173): 4.8e-28: 118: 15.08
+	Hs
		924216 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06